A. Burt, M. Coulibaly, A. Crisanti, A. Diabate and J. K. Kayondo,
Journal of Responsible Innovation,
5:S66-S80.
2018.
Despite impressive progress, malaria continues to impose a substantial burden of mortality and morbidity, particularly in sub-Saharan Africa, and new tools will be needed to achieve elimination. Gene drive is a natural process by which some genes are inherited at a greater-than-Mendelian rate and can spread through a population even if they cause harm to the organisms carrying them. Many different synthetic gene drive systems have been proposed to suppress the number of mosquitoes and/or reduce vector competence. As with any control measure, due attention should be paid to the possible evolution of resistance. No gene drive construct has yet been reported that is ‘field-ready’ for release, and when such constructs are developed, they should be assessed on a case-by-case basis. Gene drive approaches to vector control promise to have a number of key features that motivate their continued development, and scrutiny, by all concerned.
https://www.geneconvenevi.org/wp-content/uploads/2020/04/Journal-of-Responsible-Innovation-5.png300300David Obrochta/wp-content/uploads/2019/10/GC-color-logo-for-header-3277-x-827-1030x260.pngDavid Obrochta2018-01-24 15:40:222020-08-14 15:43:01Gene drive to reduce malaria transmission in sub-Saharan Africa