Sterility introduced by release of genetically altered males to a domestic population of Aedes aegypti at the Kenya coast

P. T. McDonald, W. Hausermann and N. Lorimer,  Am J Trop Med Hyg,  26:553-61. 1977.

A decade ago the concept of the sterile insect release method (SIRM) of control was generally limited to the induction of sterility through either radiation or chemical treatment. Since then the concept of genetic control has broadened to in dude the SIRM of natural sterility as well as genetic manipulation for replacement.’ Today there are a variety of preliminary endeavors to investigate the potential of genetic control for harmful insects. Our project at Mombasa, Kenya represents one of the first field trials of genetic control through the more recently developed methods of natural sterility, in this case trans location heterozygotes.

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