Con
Gene Drives on the Horizon: Advancing Science, Navigating Uncertainty, and Aligning Research with Public ValuesU. S. National Academies of Sciences, Engineering, and Medicine, The National Academies Press, 2016.Scientists have studied gene drives for more than 50 years. The development of a powerful genome editing tool in 2012, CRISPR/Cas9,1 led to recent breakthroughs in gene drive research that built on that half century’s worth of knowledge, and stimulated new discussion of the ... Keywords: Gene drive, GMO, mosquitoes, opinion, Uganda |
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Opinion: Is CRISPR-based gene drive a biocontrol silver bullet or global conservation threat?Webber, BLR, S.; Edwards, O. R., Proceedings of the National Academy of Sciences of the United States of America, 112:10565-10567. 2015.Scientists have recognized the potential for applying gene drive technologies to the control of invasive species for several years, yet debate about the application of gene drive has been primarily restricted to mosquitoes. Recent developments in clustered regularly interspaced ... Keywords: Gene drive, GMO, mosquitoes, opinion, Uganda |
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Concerning RNA-guided gene drives for the alteration of wild populationsEsvelt, KMS, Andrea L.; Catteruccia, Flaminia; Church, George M., eLife, 3:e03401. 2014.Gene drives may be capable of addressing ecological problems by altering entire; populations of wild organisms, but their use has remained largely theoretical due to technical; constraints. Here we consider the potential for RNA-guided gene drives based on the CRISPR; nuclease ... Keywords: Gene drive, GMO, mosquitoes, opinion, Uganda |
Contact
David O’Brochta
Foundation for the
National Institutes of Health
geneconvenevi@fnih.org
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