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Concerning RNA-guided gene drives for the alteration of wild populations Esvelt, KMS, Andrea L.; Catteruccia, Flaminia; Church, George M.,  eLife,  3:e03401. 2014. Gene drives may be capable of addressing ecological problems by altering entire; populations of wild organisms, but their use has remained largely theoretical due to technical; constraints. Here we consider the potential for RNA-guided gene drives based on the CRISPR; nuclease ... Keywords: extinction, gene drive synthetic, mice, mosquito, opinions, policy, public health, risks