An archive of those genetic biocontrol and gene drive-related webinars.
As part of the GeneConvene Global Collaborative‘s interests and efforts to support and promote learning and discussion around genetic biocontrol and gene drive technologies and associated issues, it hosts webinars regularly. Although ranging in subject matter, all webinars relate to genetic biocontrol directly or indirectly.
The Virtual Institute also aggregates webinars related to gene drive and genetic biocontrol that were organized and hosted by others and that collection can be viewed HERE.
Emerging Gene Drive Applications Spring 2023
Emerging Gene Drive Applications
Tags: Agriculture, Arbovirus, Gene drive, Gene drive synthetic, Invasive speciesDavid O'Brochta, 2023.
GeneConvene Global Collaborative
Webinar Series:
Emerging Gene Drive Applications 2023
February 15, 22, March 15, April 19, 26, May 10 2023
11 am- 12:30pm
(Washington, D.C.)
Gene drive systems are being engineered in the laboratory and in some cases shown to be effective at rapidly altering target-gene frequencies in experimental populations. Much of this foundational work has been conducted in insects in the laboratory. This webinar series will focus on emerging potential applications of gene drive technology in a wide variety of organisms. These webinars are intended to inform audiences of the rationale for these development efforts, the current state of research and development and outstanding challenges.
February 15, 2023 |
Towards a CRISPR/Cas9 gene drive in the Diamondback moth, Plutella xylostella |
Speaker: Dr. Timothy Harvey-Samuel, The Pirbright Institute |
A Table of Contents is available when viewed on YouTube.
February 22, 2023 |
Controlling schistosomiasis with gene drive snail immunity |
Speaker: Dr. Richard Grewelle, Stanford University |
A Table of Contents is available when viewed on YouTube.
March 15, 2923 |
Therapeutic Interfering Particles(TIPs): Discovery & Development of One-shot, Escape-resistant Antivirals |
Speaker: Dr. Leor Weinberger, University of California, San Francisco |
A Table of Contents is available when viewed on YouTube.
April 19, 2023 |
A sustainable synthetic biology approach for the control of the invasive golden mussel (Limnoperna fortunei) |
Speaker: Dr. Mauro Rebelo, Instituto de Biofísica Carlos Chagas Filho |
A Table of Contents is available when viewed on YouTube.
April 26, 2023 |
Developing safeguarding CRISPR-Cas9 gene drive in the plant pathogenic fungus, Sphaerulina musiva, to mitigate Populus diseases. |
Speaker: Dr. Joanna Tannous, Oak Ridge National Laboratory |
A Table of Contents is available when viewed on YouTube.
May 10, 2023 |
Can CRISPR/Cas-mediated genetic control strategies be developed and applied to glassy-winged sharpshooter and whitefly, hemipteran pests of agriculture? |
Speaker: Dr. Peter Atkinson, University of California, Riverside |
A Table of Contents is available when viewed on YouTube.
Laboratory Containment of Arthropods Capable of Gene Drive: Best Practices and RecommendationsOctober 2022
Laboratory Containment of Arthropods Capable of Gene Drive: Best Practices and Recommendations
Tags: Containment, Gene drive, Gene drive synthetic, Risk and safetyHector Quemada, GeneConvene Global Collaborative, 2022.
GeneConvene Global Collaborative
Webinar Series:
Laboratory Containment of Arthropods Capable of Gene Drive: Best Practices and Recommendations
October 13, 2022
11 am- 12:30pm
(Washington, D.C.)
This webinar is presented by members of the American Society of Tropical Medicine and Hygiene’s American Committee of Medical Entomologists who were involved in drafting a recent Addendum to the ASTMH’s Arthropod Containment Guidelines that specifically consider arthropods with gene drive systems. https://www.liebertpub.com/doi/10.1089/vbz.2021.0035
A Table of Contents is available when viewed on YouTube.
Wolbachia Biology, Mechanisms and Applications October-November 2022
Wolbachia Biology, Mechanisms and Applications 2022
Tags: Aedes, Cytoplasmic incompatibility, Dengue, Genetic biocontrol, Population modification/replacement, Population suppression, WolbachiaDavid O'Brochta, GeneConvene Global Collaborative, 2022.
GeneConvene Global Collaborative
Webinar Series:
Wolbachia Biology, Mechanisms and Applications 2022
October 12, 19, 26, November 9, 23, 2022
11 am- 12:30pm
(Washington, D.C.)
This is s series of 5 webinars by experts in the field in which key aspects of the biology of Wolbachia are explored such as Cytoplasmic Incompatibility and Anti-Virus effects. In addition the genomic interactions arising from the close association of these intracellular bacteria are explored and the biology of Wolbachia in populations. Finally, these studies are driven in part by the potential Wolbachia has to serve as an agent of insect control – particularly vectors of human pathogenic viruses.
October 12, 2022 |
Deploying Wolbachia for dengue control in Aedes aegypti |
Speaker: Dr. Thomas Ant, University of Glasgow |
A Table of Contents is available when viewed on YouTube.
October 19, 2022 |
Understanding the Cellular and Molecular Mechanism of Wolbachia-mediated Cytoplasmic Incompatibility |
Speaker: Dr. Rupinder Kaur, Pennsylvania State University |
A Table of Contents is available when viewed on YouTube.
October 26, 2022 |
On the origin and global spread of Wolbachia, and its relevance for human health |
Speaker: Dr. Brandon Cooper, University of Montana |
A Table of Contents is available when viewed on YouTube.
November 9, 2022 |
Wolbachia endosymbiosis and lateral gene transfer |
Speaker: Dr. Julie Dunning-Hotopp, University of Maryland School of Medicine |
A Table of Contents is available when viewed on YouTube.
November 23, 2022 |
Identifying the mechanisms of Wolbachia-mediated virus inhibition |
Speaker: Dr. Irene Garcia Newton, University of Indiana, Bloomington |
A Table of Contents is available when viewed on YouTube.
Demystifying the Convention on Biological Diverity April-May 2022
Demystifying the Convention on Biological Diversity – Seven Videos
Tags: Biodiversity/Conservation, Gene drive synthetic, Synthetic biologyHector Quemada and David O'Brochta, GeneConvene Global Collaborative, 2022.
Genetic Drive Systems in Nature- March-April 2022
Genetic Drive Systems in Nature
Tags: Selfish genetic elements, Transmission distortionDavid O'Brochta and Hector Quemada, GeneConvene Global Collaborative, 2022.
GeneConvene Global Collaborative
Webinar Series:
Genetic Drive Systems in Nature
March 2, 9, 16, 30, April 6 , 2022
11 am- 12:30pm
(Washington, D.C.)
Intra genomic genetic conflicts are ubiquitous in nature and have shaped and continue to shape the evolution of plants, animals, and microbes. These conflicts can result in preferential transmission – drive – of genes, various genetic elements, and even whole chromosomes. Interest in drive systems extends beyond the basic sciences to technologists who are exploring natural and synthetic drives as agents to suppress or modify species in nature. This webinar series will explore the variety of drive systems found in nature, mechanisms responsible for drive and impacts of drive on behavior and evolution..
March 2, 2022 |
Cell Biology of Female Meiotic Drive in Mice |
Speaker: Dr. Takashi Akera, National Heart Lung and Blood Institute |
A Table of Contents is available when viewed on YouTube.
March 9, 2022 |
Meiotic Drive and Satellite DNA in Drosophila |
Speaker: Dr. Amanda Larracuente, University of Rochester |
A Table of Contents is available when viewed on YouTube.
March 16, 2022 |
Supernumerary B Chromosomes: Champions of Chromosome Drive |
Speaker: Dr. Andreas Houben, The Leibniz Institute of Plant Genetics and Crop Plant Research |
A Table of Contents is available when viewed on YouTube.
March 24, 2022 |
Selfish Genes, Sex Chromosomes and Speciation in Drosophila |
Speaker: Dr. Daven Presgraves, University of Rochester |
A Table of Contents is available when viewed on YouTube.
March 30, 2022 |
Ecology of the t-haplotype: A Natural Gene Drive System in House Mice |
Speaker: Dr. Anna Lindholm, University of Zurich |
A Table of Contents is available when viewed on YouTube.
April 6, 2022 |
WTF Spore Killers |
Speaker: Dr. Sarah Zanders, Stowers Institute |
A Table of Contents is available when viewed on YouTube.
Invasive Species Management: Informing Gene Drive- October-November 2021
Invasive Species Management: Informing Gene Drive Considerations
Tags: Field trials, Gene drive, Genetic biocontrol, Invasive species, RodentsDavid O'Brochta and Hector Quemada, GeneConvene Global Collaborative, 2021.
GeneConvene Global Collaborative
Webinar Series:
Invasive Species Management:
Informing Gene Drive Considerations
October 13, 27, November 3
11 am- 12:30pm
(Washington, D.C.)
The management, control and elimination of invasive species involves solving problems that have analogs to those anticipating the use of gene drive technologies to control and eliminate malaria in Africa. Avoiding unintended consequences from interventions designed to reduce or remove a species from an ecosystem has parallels in some applications of gene drive technologies. Monitoring and surveilling for the movement of invasive species is critical for making management decisions and methods and approaches that have been devised to deal with challenges such as large geographic areas, low species densities, limited resources to name just a few could inform thinking about monitoring and surveillance of gene drive-containing organisms. This series of webinars by invasive species specialists will feature research into how these challenges are being successfully addressed.
Each seminar will be 45-50 minutes in length followed by questions and answers.
Not a convenient time? Each webinar will be recorded and promptly posted on the GeneConvene Virtual Institute, and questions will be taken for 48 hours after the initial presentation. The speaker’s responses will be attached to the original presentation.
October 13, 2021 |
Conservation in the Anthropocene: can community ecology help avoid unintended outcomes and improve conservation success? |
Speaker: Dr. Dean Pearson,USDA/ Forest Service |
A Table of Contents is available when viewed on YouTube.
October 27, 2021 |
Targeting Surveillance for Invasive Agricultural Pests and Diseases |
Speaker: Dr.Gericke Cook, USDA/ APHIS/ VS/ CEAH |
A Table of Contents is available when viewed on YouTube.
November 3, 2021 |
Monitoring gene drive vertebrates in the environment
|
Speaker: Dr. Toni Piaggio, USDA/ NWRC. |
A Table of Contents is available when viewed on YouTube.
Controlling Gene Drives: - September-October 2021
Controlling Gene Drives
David O'Brochta and Hector Quemada, GeneConvene Global Collaborative, 2021.GeneConvene Global Collaborative
Webinar Series:
Controlling Gene Drives
September 22, 29, October 6
11 am- 12:30pm
(Washington, D.C.)
Some gene drive technologies being explored in the laboratory for possible use in the control and elimination of malaria in Africa are predicted to efficiently spread and persist indefinitely following their initial release into an environment containing the targeted mosquito species. While the autonomous properties of some gene drive technologies are desirable features that are expected to make them effective at controlling hard to reach populations of targeted mosquitoes and to provide sustained control with minimal additional inputs, the ability to control spread and persistence remains important. This series of webinars will feature researchers and developers exploring various control options for gene drive technologies.
September 22, 2021 |
Development of Gene Drives and a Method to Block Them in Anopheles gambiae |
Speaker: Dr. Chrysanthi Taxiarchi, Imperial College London. |
A Table of Contents is available when viewed on YouTube.
September 29, 2021 |
Lessons Learned from Neutralizing Drives |
Speaker: Dr.Ethan Bier, University of California, San Diego. |
A Table of Contents is available when viewed on YouTube.
October 6, 2021 |
Chemical approaches to control and enhance CRISPR-based technologies |
Speaker: Dr. Amit Choudhary, Harvard University. |
A RECORDING OF THIS WEBINAR IS CURRENTLY UNAVAILABLE
Ecological Relationships of Mosquito Disease Vectors: Anticipating Risk Assessment of Gene Drive TechnologiesApril-May 2021
Ecological Relationships of Mosquito Disease Vectors: Anticipating Risk Assessment of Gene Drive Technologies
Tags: Ecology, Gene drive synthetic, Risk assessmentStephanie James, Hector Quemada and David O'Brochta, GeneConvene Global Collaborative, 2021.
GeneConvene Global Collaborative
Webinar Series:
Ecological Relationships of Mosquito Disease Vectors:
Anticipating Risk Assessment of Gene Drive Technologies
April 21, 28, May 5, 12, 19
11 am- 12:30pm
(Washington, D.C.)
An often-raised concern for the development of genetically modified mosquito technologies, particularly those involving gene drive, as tools to prevent disease transmission is the limitation of our understanding of the roles these species may play within the ecosystem. This series of webinars begins to explore what is known about the ecological relationships of mosquito vectors with regard to major types of species interactions. The speakers also will describe some of the methods by which potential interactions that may impact human or animal health and the environment can be examined in the context of case-by-case risk assessment and safety testing.
Each seminar will consist of two 30-minutes presentation followed by questions and answers.
There will be 2 speakers per meeting. Each will speak for 30 minutes followed by a joint question and answer session.
Not a convenient time? Each webinar will be recorded and promptly posted on the GeneConvene Virtual Institute,
April 21, 2021 |
Theme: Interspecific competition |
Competition, coexistence, and exclusion among Aedes mosquitoes: insights from ecological theory.Speaker: Steven Juliano, Ph.D. Illinois State University |
|
A systematic review assessing the potential for release of vector species from competition following insecticide-based population suppression of Anopheles species in Africa.Speaker: John Connolly, Ph.D. Imperial College London |
Video Table of Contents available on YouTube
References Related Dr. Juliano’s Presentation. (on this page)
References Related Dr. Connolly’s Presentation. (on this page)
April 28, 2021 |
Theme: Non-target effects and predator/competitor interactions |
Understanding the risks vs benefits of classical biological control programs for crop pests: Case studies from AfricaSpeaker: Ivan Rwomushana, Ph.D. CABI, Nairobi, Kenya |
|
What does eat an Anopheles ? Potential ecosystem effects of focused species reductions.Speaker: Tilly Collins, Ph.D. Imperial College London |
Video Table of Contents available on YouTube
References Related Dr. Rwomushana’s Presentation. (on this page)
References Related Dr. Collins’ Presentation. (on this page)
May 5, 2021 |
Theme: Symbiosis and mutualism |
Mosquito-microbe interactions: are there implications for gene drives?.Speaker: Nsa Dada,, Ph.D. Mosquito Microbiome Consortium |
|
Pollination of plants by mosquitoes: Do some plants depend on disease vectors to transfer their pollen?Speaker: Woody Foster, Ph.D. Ohio State University |
Video Table of Contents available on YouTube
References Related Dr. Dada’s Presentation. (on this page)
References Related Dr. Foster’s Presentation. (on this page)
May 12, 2021 |
Theme: Hybridization and gene flow among African Anopheles species |
How likely is Anopheles hybridization and introgression?Speaker: ora Besansky, Ph.D. Notre Dame University |
|
Assessing the impact of landscape features on gene flow of malaria mosquitoes in Kenya.Speaker: Guiyun Yan, Ph.D. University of California, Irvine |
Video Table of Contents available on YouTube
References Related Dr. Besansky’s Presentation. (on this page)
References Related Dr. Yan’s Presentation. (on this page)
May 19 2021 |
Theme: Parasitism and vector competence |
Laboratory methods to study mosquito infections with pathogens.Speaker: Stephen Higgs, Ph.D. Kansas State University |
|
Relative potential for harm of pathogens vectored by Anopheles gambiae s.l.Speaker: Geoff Hosack, Ph.D. CSIRO |
Video Table of Contents available on YouTube
References Related Dr. Higgs’s Presentation. (on this page)
References Related Dr. Hosack’s Presentation. (on this page)
ADDITIONAL REFERENCES
Fader, J. E., & Juliano, S. A. (2013). An empirical test of the aggregation model of coexistence and consequences for competing container-dwelling mosquitoes. Ecology, 94(2), 478-488. https://doi.org/10.1890/12-0123.1Gorman, K., Young, J., Pineda, L., Marquez, R., Sosa, N., Bernal, D., . . . Caceres, L. (2016). Short-term suppression of Aedes aegypti using genetic control does not facilitate Aedes albopictus. Pest Management Science, 72(3), 618-628. https://doi.org/10.1002/ps.4151
Kraemer, M. U. G., Sinka, M. E., Duda, K. A., Mylne, A. Q. N., Shearer, F. M., Barker, C. M., . . . Hay, S. I. (2015). The global distribution of the arbovirus vectors Aedes aegypti and Ae. albopictus. Elife, 4, 18. https://doi.org/10.7554/eLife.08347
Leisnham, P. T., LaDeau, S. L., & Juliano, S. A. (2014). Spatial and Temporal Habitat Segregation of Mosquitoes in Urban Florida. Plos One, 9(3), 10. https://doi.org/10.1371/journal.pone.0091655
Murrell, E. G., Damal, K., Lounibos, L. P., & Juliano, S. A. (2011). Distributions of Competing Container Mosquitoes Depend on Detritus Types, Nutrient Ratios, and Food Availability. Annals of the Entomological Society of America, 104(4), 688-698. https://doi.org/10.1603/an10158
Gillies, M. T., & Smith, A. (1960). The effect of a residual house-spraying campaign in East Africa on species balance in the Anopheles funestus group. The replacement of A. funestus Giles by A. rivulorum Leeson. Bulletin of Entomological Research, 51(2), 243-252. https://doi.org/10.1017/S0007485300057953
Qureshi, A., & Connolly, J. B. (2021). A systematic review assessing the potential for release of vector species from competition following insecticide-based population suppression of Anopheles species in Africa. .Parasites Vectors, 14, 462 https://doi.org/10.1186/s13071-021-04975-0
Russell, T. L., Govella, N. J., Azizi, S., Drakeley, C. J., Kachur, S. P., & Killeen, G. F. (2011). Increased proportions of outdoor feeding among residual malaria vector populations following increased use of insecticide-treated nets in rural Tanzania. Malaria Journal, 10, 10. https://doi.org/10.1186/1475-2875-10-80
Sougoufara, S., Harry, M., Doucoure, S., Sembene, P. M., & Sokhna, C. (2016). Shift in species composition in the Anopheles gambiae complex after implementation of long-lasting insecticidal nets in Dielmo, Senegal. Medical and Veterinary Entomology, 30(3), 365-368. https://doi.org/10.1111/mve.12171
Zhou, G. F., Afrane, Y. A., Vardo-Zalik, A. M., Atieli, H., Zhong, D. B., Wamae, P., . . . Yan, G. Y. (2011). Changing Patterns of Malaria Epidemiology between 2002 and 2010 in Western Kenya: The Fall and Rise of Malaria. Plos One, 6(5), 12. https://doi.org/10.1371/journal.pone.0020318
References Related Dr. Rwomushana’s Presentation. go back^
Barratt, B. I. P., Moeed, A., & Malone, L. A. (2006). Biosafety assessment protocols for new organisms in New Zealand: Can they apply internationally to emerging technologies? Environmental Impact Assessment Review, 26(4), 339-358. https://doi.org/https://doi.org/10.1016/j.eiar.2005.11.008
Cock, M. J. W., Lenteren, J. C. v., Brodeur, J., Barratt, B. I. P., Bigler, F., Bolckmans, K., . . . Parra, J. R. P. (2009). The use and exchange of biological control agents for food and agriculture. Food and Agriculture Organization, Commission on Genetic Resources for Food and Agriculture COMMISSION ON GENETIC RESOURCES FOR FOOD AND AGRICULTURE.
Neuenschwander, P., Herren, H. R., Harpaz, I., Badulescu, D., Akingbohungbe, A. E., Wood, R. K. S., & Way, M. J. (1988). Biological control of the cassava mealybug, Phenacoccus manihoti by the exotic parasitoid Epidinocarsis lopezi in Africa. Philosophical Transactions of the Royal Society of London. B, Biological Sciences, 318(1189), 319-333. https://doi.org/10.1098/rstb.1988.0012
Russell, T. L., Govella, N. J., Azizi, S., Drakeley, C. J., Kachur, S. P., & Killeen, G. F. (2011). Increased proportions of outdoor feeding among residual malaria vector populations following increased use of insecticide-treated nets in rural Tanzania. Malaria Journal, 10, 10. https://doi.org/10.1186/1475-2875-10-80
Secretariat of the International Plant Protection Convention. (2005). ISPM 3: Guidelines for the export, shipment, import and release of biological control agents and other beneficial organisms. International Plant Protection Convention.
References Related Dr. Collins’ Presentation. go back^
American Mosquito Control Association. (2021). Do purple martins help reduce mosquitoes? Retrieved from https://www.mosquito.org/page/FAQ#Do%20Purple%20Martins%20help%20reduce%20mosquitoes?
Bohmann, K., Monadjem, A., Lehmkuhl Noer, C., Rasmussen, M., Zeale, M. R. K., Clare, E., . . . Gilbert, M. T. P. (2011). Molecular Diet Analysis of Two African Free-Tailed Bats (Molossidae) Using High Throughput Sequencing. Plos One, 6(6), e21441. https://doi.org/10.1371/journal.pone.0021441
Collins, C. M., Bonds, J. A. S., Quinlan, M. M., & Mumford, J. D. (2019). Effects of the removal or reduction in density of the malaria mosquito, Anopheles gambiae s.l., on interacting predators and competitors in local ecosystems. Medical and Veterinary Entomology, 33(1), 1-15. https://doi.org/https://doi.org/10.1111/mve.12327
Jackson, R. R., Deng, C., & Cross, F. R. Convergence between a mosquito-eating predator’s natural diet and its prey-choice behaviour. Royal Society Open Science, 3(12), 160584. https://doi.org/10.1098/rsos.160584
Stephens, D. W., Brown, J. S., & Ydenberg, R. C. (Eds.). (2007). Foraging: Behavior and Ecology. Chicago, IL: The University of Chicago Press.
References Related Dr. Dada’s Presentation. go back^
Caragata, E. P., Tikhe, C. V., & Dimopoulos, G. (2019). Curious entanglements: interactions between mosquitoes, their microbiota, and arboviruses. Curr Opin Virol, 37, 26-36. https://doi.org/10.1016/j.coviro.2019.05.005
Coon, K. L., Brown, M. R., & Strand, M. R. (2016). Mosquitoes host communities of bacteria that are essential for development but vary greatly between local habitats. Mol Ecol, 25(22), 5806-5826. https://doi.org/10.1111/mec.13877
Gendrin, M., & Christophides, G. K. (2013). The Anopheles Mosquito Microbiota and Their Impact on Pathogen Transmission. In S. Manguin (Ed.), Anopheles mosquitoes – New insights into malaria vectors.
Guégan, M., Tran Van, V., Martin, E., Minard, G., Tran, F. H., Fel, B., . . . Valiente Moro, C. (2020). Who is eating fructose within the Aedes albopictus gut microbiota? Environ Microbiol, 22(4), 1193-1206. https://doi.org/10.1111/1462-2920.14915
Krajacich, B. J., Huestis, D. L., Dao, A., Yaro, A. S., Diallo, M., Krishna, A., . . . Lehmann, T. (2018). Investigation of the seasonal microbiome of Anopheles coluzzii mosquitoes in Mali. Plos One, 13(3), e0194899. https://doi.org/10.1371/journal.pone.0194899
References Related Dr. Foster’s Presentation. go back^
Foster, W. A. (2020). Pollination of plants by disease vectors: an assessment. Retrieved from https://www.geneconvenevi.org/pollination-of-plants-by-disease-vectors-a-risk-assessment/
Gary Jr, R. E., & Foster, W. A. (2004). Anopheles gambiae feeding and survival on honeydew and extra-floral nectar of peridomestic plants. Medical and Veterinary Entomology, 18(2), 102-107. https://doi.org/https://doi.org/10.1111/j.0269-283X.2004.00483.x
Gouagna, L.-C., Poueme, R. S., Dabiré, K. R., Ouédraogo, J.-B., Fontenille, D., & Simard, F. (2010). Patterns of sugar feeding and host plant preferences in adult males of An. gambiae (Diptera: Culicidae). Journal of Vector Ecology, 35(2), 267-276. https://doi.org/https://doi.org/10.1111/j.1948-7134.2010.00082.x
Müller, G. C., Beier, J. C., Traore, S. F., Toure, M. B., Traore, M. M., Bah, S., . . . Schlein, Y. (2010). Field experiments of Anopheles gambiae attraction to local fruits/seedpods and flowering plants in Mali to optimize strategies for malaria vector control in Africa using attractive toxic sugar bait methods. Malaria Journal, 9(1), 262. https://doi.org/10.1186/1475-2875-9-262
References Related Dr. Besansky’s Presentation. go back^
Fontaine, M. C., Pease, J. B., Steele, A., Waterhouse, R. M., Neafsey, D. E., Sharakhov, I. V., . . . Besansky, N. J. (2015). Extensive introgression in a malaria vector species complex revealed by phylogenomics. Science, 347(6217), 1258524. https://doi.org/10.1126/science.1258524
Mallet, J., Besansky, N., & Hahn, M. W. (2016). How reticulated are species? Bioessays, 38(2), 140-149. https://doi.org/https://doi.org/10.1002/bies.201500149
Pombi, M., Kengne, P., Gimonneau, G., Tene-Fossog, B., Ayala, D., Kamdem, C., . . . Costantini, C. (2017). Dissecting functional components of reproductive isolation among closely related sympatric species of the Anopheles gambiae complex. Evolutionary Applications, 10(10), 1102-1120. https://doi.org/https://doi.org/10.1111/eva.12517
Small, S. T., Labbé, F., Lobo, N. F., Koekemoer, L. L., Sikaala, C. H., Neafsey, D. E., . . . Besansky, N. J. (2020). Radiation with reticulation marks the origin of a major malaria vector. Proceedings of the National Academy of Sciences, 117(50), 31583. https://doi.org/10.1073/pnas.2018142117
Thawornwattana, Y., Dalquen, D., & Yang, Z. (2018). Coalescent Analysis of Phylogenomic Data Confidently Resolves the Species Relationships in the Anopheles gambiae Species Complex. Molecular Biology and Evolution, 35(10), 2512-2527. https://doi.org/10.1093/molbev/msy158
References Related Dr. Yan’s Presentation. go back^
Hemming-Schroeder, E., Lo, E., Salazar, C., Puente, S., & Yan, G. (2018). Landscape Genetics: A Toolbox for Studying Vector-Borne Diseases. Frontiers in Ecology and Evolution, 6(21). https://doi.org/10.3389/fevo.2018.00021
Hemming-Schroeder, E., Zhong, D., Machani, M., Nguyen, H., Thong, S., Kahindi, S., . . . Yan, G. (2020). Ecological drivers of genetic connectivity for African malaria vectors Anopheles gambiae and An. arabiensis. Scientific Reports, 10(1), 19946. https://doi.org/10.1038/s41598-020-76248-2
Lehmann, T., Hawley, W. A., Grebert, H., Danga, M., Atieli, F., & Collins, F. H. (1999). The Rift Valley complex as a barrier to gene flow for Anopheles gambiae in Kenya. Journal of Heredity, 90(6), 613-621. https://doi.org/10.1093/jhered/90.6.613
North, A. R., Burt, A., & Godfray, H. C. J. (2019). Modelling the potential of genetic control of malaria mosquitoes at national scale. Bmc Biology, 17(1), 26. https://doi.org/10.1186/s12915-019-0645-5
References Related Dr. Higgs’s Presentation. go back^
American Committee of Medical, E., American Society of Tropical, M., & Hygiene. (2019). Arthropod Containment Guidelines, Version 3.2. Vector-Borne and Zoonotic Diseases, 19(3), 152-173. https://doi.org/10.1089/vbz.2018.2431
Crampton, J. M., Beard, C. B., & Louis, C. (Eds.). (1997). The Molecular Biology of Insect Disease Vectors: A Methods Manual. Dordrecht: Springer.
Miura, K., Deng, B., Tullo, G., Diouf, A., Moretz, S. E., Locke, E., . . . Long, C. A. (2013). Qualification of Standard Membrane-Feeding Assay with Plasmodium falciparum Malaria and Potential Improvements for Future Assays. PloS One, 8(3), e57909. https://doi.org/10.1371/journal.pone.0057909
References Related Dr. Hosack’s Presentation. go back^
Dutra, Heverton Leandro C., Rocha, Marcele N., Dias, Fernando Braga S., Mansur, Simone B., Caragata, Eric P., & Moreira, Luciano A. (2016). Wolbachia Blocks Currently Circulating Zika Virus Isolates in Brazilian Aedes aegypti Mosquitoes. Cell Host & Microbe, 19(6), 771-774. https://doi.org/https://doi.org/10.1016/j.chom.2016.04.021
Hayes, K. R., Peel, D., Eagles, D., & Hosack, G. R. (2020). Structured prioritisation of human and animal pathogens for the purpose of scoping risk assessments of genetic control strategies for malaria vectors in sub-Saharan Africa. Retrieved from https://fnih.org/sites/default/files/pdf/Pathogen_prioritisation_final_report_v6.pdf
Hosack, G. R., Ickowicz, A., & Hayes, K. R. Quantifying the risk of vector-borne disease transmission attributable to genetically modified vectors. Royal Society Open Science, 8(3), 201525. https://doi.org/10.1098/rsos.201525
Keeney, R. L., & Raiffa, H. (1993). Decisions with Multiple Objectives: Preferences and Value Trade-Offs. Cambridge: Cambridge University Press.
Ye, Y. H., Carrasco, A. M., Frentiu, F. D., Chenoweth, S. F., Beebe, N. W., van den Hurk, A. F., . . . McGraw, E. A. (2015). Wolbachia Reduces the Transmission Potential of Dengue-Infected Aedes aegypti. Plos Neglected Tropical Diseases, 9(6), e0003894. https://doi.org/10.1371/journal.pntd.0003894
Ecological Modeling in Risk Assessment of Gene Drives - March 2021
Ecological Modeling in Risk Assessment of Gene Drives
Tags: Gene drive synthetic, Modeling, Regulation, Risk assessmentHector Quemada and David O'Brochta, 2021.
GeneConvene Global Collaborative
Webinar Series:
Ecological Modeling in Risk Assessment
of Gene Drives
March 10, 17, 24, 31
11 am- 12:30pm
(Washington, D.C.)
Risk assessment of gene drive organisms will require the development of new tools to complement established risk assessment methodologies for genetically modified organisms with the paradigm for risk assessment agreed to by most countries in the world being the Cartagena Protocol on Biosafety. One recognized need is the use of models to help predict the ecological consequences of released gene drive organisms. Unlike non-gene drive organisms, which can be limited in time and space and therefore provide data in small scale tests that can be relevant to large scale releases, the potential for large-scale spread gene drive-containing organisms even from a limited release and even in well-isolated trials, means that risk assessors will need to consider models and forecasts in their decision-making.
To date, this work has only started to receive attention. This series of four presentations deals with the development and use of models in ecology generally and some of these presentations will also deal with the use of models specifically to assess the ecological impacts of gene drive organisms.
Each seminar will be 45-50 minutes in length followed by questions and answers.
Not a convenient time? Each webinar will be recorded and promptly posted on the GeneConvene Virtual Institute, and questions will be taken for 48 hours after the initial presentation. The speaker’s responses will be attached to the original presentation.
March 10, 2021 |
Use of models in environmental risk assessment for gene drive insects |
Speakers: Drs. John Mumford1 and Michael Bonsall2, 1Imperial College, London 2Oxford University |
March 17, 2021 |
Qualitative Mathematical Modelling of Complex Systems |
Speakers: Dr. Jeffery Dambacher, Commonwealth Scientific and Industrial Research Organization |
March 24, 2021 |
Embracing dynamic models for gene drive management |
Speakers: Drs. Kim Pepin and Andrew Golnar, USDA-Animal and Plant Health Inspection Service |
March 31, 2021 |
The application of quantitative ecological risk assessment to the release of gene drives |
Speaker: Dr. Wayne Landis, Western Washington University |
Genetic Biocontrol - February 2021
Genetic Biocontrol Webinars
Tags: Genetic biocontrol, Incompatible insect technique, Oxitec, Sterile insect technique (SIT), WolbachiaDavid O'Brochta and Hector Quemada, GeneConvene Global Collaborative, 2021.
GeneConvene Global Collaborative
Webinar Series:
Genetic Biocontrol
Feb 3, 10, 17, 24
11 am- 12:30pm
(Washington, D.C.)
In the mid 20th century various ideas emerged concerning how genetics and genetic principles could be directly applied to age-old problems of managing insects that threaten food security and public health. This series of webinars will explore the current state-of-the-art of what has been termed genetic control, genetic pest management and genetic biocontrol. It will cover the use of sterility, conditional dominant lethality and Wolbachia-induced cytoplasmic incompatibility. Gene drive, another type of genetic biocontrol, will not be covered in this series; it was recently the focus of webinar series dedicated to the topic. This webinar series is a scientific forum where one will hear and learn about the latest research in this area of applied genetics from those conducting the research.
Each seminar will be 45-50 minutes in length followed by questions and answers.
Not a convenient time? Each webinar will be recorded and promptly posted on the GeneConvene Virtual Institute, and questions will be taken for 48 hours after the initial presentation. The speaker’s responses will be attached to the original presentation.
Feb 3, 2021 |
Self-Limiting Insects for Accessible and Sustainable Biological Pest Management |
Speakers: Drs. Kevin Gorman and Nathan Rose, Oxitec, Ltd. |
Feb 10, 2021 |
Using Wolbachia to control arboviruses |
Speaker: Dr. Luciano Moreira, Fundação Oswaldo Cruz and World Mosquito Program |
Feb 14, 2021 |
Development of the SIT package against Aedes mosquitoes: progress and challenges |
Speakers: Drs. Jeremy Bouyer and Kostas Bourtzis, Joint FAO/IAEA Programme Nuclear Techniques in Food and Agriculture |
Feb 24 2021 |
Wolbachia bacteria as a ‘pesticide’ against mosquito populations |
Speakers: Dr. Stephen Dobson, University of Kentucky and MosquitoMate, Inc. Dr. Johanna Ohm, Verily Life Sciences |
Engineered Gene Drives: Policy and Regulatory Considerations - October-December 2020
Engineered Gene Drives: Policy and Regulatory Considerations Webinar Series by The GeneConvene Global Collaborative October-December 2020 – Four Videos
Tags: Gene drive synthetic, Governance, Policy, Regulation, Risk and safety, Risk assessment, Stakeholder engagementHector Quemada and David O'Brochta, GeneConvene Global Collaborative, 2020.
Engineered Gene Drives: State of Research - September-October 2020
Engineered Gene Drives: State of Research Webinar Series by The GeneConvene Global Collaborative September-October 2020
Tags: CRISPR, Gene drive synthetic, Genetic incompatibilities, Population modification/replacement, Population suppression, Replicator/site directed nucleaseDavid O'Brochta and Hector Quemada, GeneConvene Global Collaborative, 2020.
September 9,16,23,30, October 7, 14
11 am- 12:30pm
(Washington, D.C. -GMT -5)
This was a series of public scientific and technical seminars by researchers actively involved in the research and development of engineered gene drive and related systems. Presentations were aimed at other researchers and scientists, highlighting the latest investigations in this area of applied genetics.
Sept. 9 Gene-drive systems for mosquito population modification. Anthony James, Ph.D., University of California, Irvine
Sept. 16 Manipulation wild populations using Cleave and Rescue (ClvR) selfish genetic elements. Bruce Hay, Ph.D., California Institute of Technology (Caltech)
Sept 23 Advanced genetic control of human disease vectors. Omar Akbari, Ph.D., University of California, San Diego
Sept 30 Transmission Zero: Converting malaria vector mosquitoes into non-vectors via minimal genetic modifications. George Christophides, Ph.D., Imperial College, London
Oct 7 Anoheles gambiae population suppression gene drive technologies. Andrea Crisanti, Ph.D. Imperial College, London
Oct 14 Engineered Genetic Incompatibility- species-like barriers to sexual reproducing insects. Michael Smanski, Ph.D., University of Minnesota