
Keywords: adaptation
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Requirements for effective malaria control with homing endonuclease genesDeredec, AG, H. C. J.; Burt, A., Proceedings of the National Academy of Sciences of the United States of America, 108:e874-e880. 2011.![]() Malaria continues to impose a substantial burden on human health. We have previously proposed that biological approaches to control the mosquito vector of disease could be developed using homing endonuclease genes (HEGs), a class of selfish or parasitic gene that exists naturally ... Keywords: adaptation, distribution, DNA, elements, Evolution, gene drive ecology, gene drive evolution, gene drive natural, gene-sequences, group-i introns, homing endonuclease, horizontal (lateral) transfer (transmission), identification, intein, phylogenetic analysis, plants, protein-splicing domain, rna, selfish gene, VDE, yeast, yeast saccharomyces-cerevisiae |
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Adaptation for horizontal transfer in a homing endonucleaseKoufopanou, VG, M. R.; Burt, A., Molecular Biology and Evolution, 19:239-246. 2002.![]() Selfish genes of no function other than self-propagation are susceptible to degeneration if they become fixed in a population. and regular transfer to new species may be the only means for their long-term persistence. To test this idea we surveyed 24 species of yeast for VDE, a ... Keywords: adaptation, distribution, DNA, elements, Evolution, gene drive ecology, gene drive evolution, gene drive natural, gene-sequences, group-i introns, homing endonuclease, horizontal (lateral) transfer (transmission), identification, intein, phylogenetic analysis, plants, protein-splicing domain, rna, selfish gene, VDE, yeast, yeast saccharomyces-cerevisiae |

Contact
David O’Brochta
Foundation for the
National Institutes of Health
geneconvenevi@fnih.org
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