Keywords: aegypti

Independent evaluation of Wolbachia infected male mosquito releases for control of Aedes aegypti in Harris County, Texas, using a Bayesian abundance estimator

S. Lozano, K. Pritts, D. Duguma, C. Fredregill and R. Connelly,  PLOS Neglected Tropical Diseases,  16:e0010907. 2022.
Among disease vectors, Aedes aegypti (L.) (Diptera: Culicidae) is one of the most insidious species in the world. The disease burden created by this species has dramatically increased in the past 50 years, and during this time countries have relied on pesticides for control and ...
Keywords: , , , , , , ,

Independent evaluation of Wolbachia infected male mosquito releases for control of Aedes aegypti in Harris County, Texas, using a Bayesian abundance estimator

S. Lozano, K. Pritts, D. Duguma, C. Fredregill and R. Connelly,  PLOS Neglected Tropical Diseases,  16:e0010907. 2022.
Author summary Aedes aegypti is one of the most important mosquito species because females can potentially carry pathogens that cause disease. These diseases have a tremendous impact worldwide making this species an important target of control. We evaluated a mosquito control ...
Keywords: , , , , , , ,

Influence of public hesitancy and receptivity on reactive behaviours towards releases of male Wolbachia-Aedes mosquitoes for dengue control

M. O. Lwin, Z. Ong, C. Panchapakesan, A. Sheldenkar, L. T. Soh, I. Chen, X. Li, W. Niah, K. Vasquez, S. Sim and L.-C. Ng,  PLOS Neglected Tropical Diseases,  16:e0010910. 2022.
Singapore, a highly urbanized Asian tropical country that experiences periodic dengue outbreaks, is piloting field releases of male Wolbachia-carrying Aedes aegyptimosquitoes with the aim of suppressing urban populations of the primary dengue vector Aedes aegypti. This study ...
Keywords: , , , , , , ,

Wolbachia inhibits ovarian formation and increases blood feeding rate in female Aedes aegypti

M.-J. Lau, P. A. Ross, N. M. Endersby-Harshman, Q. Yang and A. A. Hoffmann,  PLOS Neglected Tropical Diseases,  16:e0010913. 2022.
Author summary Wolbachia bacteria reduce the transmission of dengue and other arboviruses transmitted by their mosquito hosts once they have invaded host populations. This invasion process is being undertaken in Aedes aegypti mosquito populations throughout the world but can be ...
Keywords: , , , , , , ,

D. O. Carvalho, R. Morreale, S. Stenhouse, D. A. Hahn, M. Gomez, A. Lloyd and D. Hoel,  Parasites and Vectors,  15:405. 2022.
The sterile insect technique (SIT), which involves area-wide inundative releases of sterile insects to suppress the reproduction of a target species, has proven to be an effective pest control method. The technique demands the continuous release of sterilized insects in ...
Keywords: , , , , , , ,

New self-sexing Aedes aegypti strain eliminates barriers to scalable and sustainable vector control for governments and communities in dengue-prone environments

S. A. M. Spinner, Z. H. Barnes, A. M. Puinean, P. Gray, T. Dafa’alla, C. E. Phillips, C. Nascimento de Souza, T. F. Frazon, K. Ercit, A. Collado, N. Naish, E. Sulston, G. C. Ll. Phillips, K. K. Greene, M. Poletto, B. D. Sperry, S. A. Warner, N. R. Rose, G,  Frontiers in Bioengineering and Biotechnology,  10. 2022.
For more than 60 years, efforts to develop mating-based mosquito control technologies have largely failed to produce solutions that are both effective and scalable, keeping them out of reach of most governments and communities in disease-impacted regions globally. High pest ...
Keywords: , , , , , , ,

Assessing single-locus CRISPR/Cas9-based gene drive variants in the mosquito Aedes aegypti via single generation crosses and modeling

W. Reid, A. E. Williams, I. Sanchez-Vargas, J. Lin, R. Juncu, K. E. Olson and A. W. E. Franz,  G3 Genes|Genomes|Genetics,  2022.
Critical to the design of a single-locus autonomous GD is that the selected genomic locus is amenable to both GD and appropriate expression of the antiviral effector. In our study, we used reverse engineering to target two intergenic genomic loci, which had previously shown to be ...
Keywords: , , , , , , ,

Wolbachia Biology, Mechanisms and Applications 2022

David O'Brochta,  GeneConvene Global Collaborative,  2022.
Intracellular and extracellular symbiotic/commensal bacteria have enormous potential when manipulated and deployed appropriately to serve as agents of control of insects and the pathogens they transmit. Wolbachia, an intracellular bacteria, is a well studied system and one that ...
Keywords: , , , , , , ,

Wolbachia wAlbB inhibit dengue and Zika infection in the mosquito Aedes aegypti with an Australian background

L. E. Hugo, G. Rašić, A. J. Maynard, L. Ambrose, C. Liddington, C. J. E. Thomas, N. S. Nath, M. Graham, C. Winterford, B. M. C. R. Wimalasiri-Yapa, Z. Xi, N. W. Beebe and G. J. Devine,  PLOS Neglected Tropical Diseases,  16:e0010786. 2022.
Biological control of mosquito vectors using the endosymbiotic bacteria Wolbachia is an emerging strategy for the management of human arboviral diseases. We recently described the development of a strain of Aedes aegypti infected with the Wolbachia strain wAlbB (referred to as ...
Keywords: , , , , , , ,

Risk Assessment on the Release of Wolbachia-Infected Aedes aegypti in Yogyakarta, Indonesia

D. Buchori, A. Mawan, I. Nurhayati, A. Aryati, H. Kusnanto and U. K. Hadi,  Insects,  13. 2022.
Wolbachia-infected Aedes aegypti is the latest technology that was developed to eliminate dengue fever. The Ministry of Research and Technology of the Republic of Indonesia (Kemenristekdikti) established an expert group to identify future potential risks that may occur over a ...
Keywords: , , , , , , ,

Fitness costs of Wolbachia shift in locally-adapted Aedes aegypti mosquitoes

P. A. Ross and A. A. Hoffmann,  Environmental Microbiology,  2022.
Aedes aegypti mosquito eggs can remain quiescent for many months before hatching, allowing populations to persist through unfavorable conditions. Aedes aegypti infected with the Wolbachia strain wMel have been released in tropical and subtropical regions for dengue control. wMel ...
Keywords: , , , , , , ,

Externalities modulate the effectiveness of the Wolbachia release programme

E. E. Ooi and A. Wilder-Smith,  The Lancet Infectious Diseases,  2022.
Despite the remarkable outcome in Yogyakarta, the wMel approach also has some challenges. In particular, the extent to which ecological, weather, and other external factors influence the dissemination and establishment of wMel in complex urban environments remains unclear. ...
Keywords: , , , , , , ,

Estimating the effect of the wMel release programme on the incidence of dengue and chikungunya in Rio de Janeiro, Brazil: a spatiotemporal modelling study

G. Ribeiro dos Santos, B. Durovni, V. Saraceni, T. I. Souza Riback, S. B. Pinto, K. L. Anders, et al.,  The Lancet Infectious Diseases,  2022.
Summary Background Introgression of genetic material from species of the insect bacteria Wolbachia into populations of Aedes aegypti mosquitoes has been shown in randomised and non-randomised trials to reduce the incidence of dengue; however, evidence for the real-world ...
Keywords: , , , , , , ,

The Involvement of Atlastin in Dengue Virus and Wolbachia Infection in Aedes aegypti and Its Regulation by aae-miR-989

M. Hussain, T. Bradshaw, M. Lee and S. Asgari,  Microbiology Spectrum,  2022.
Endoplasmic reticulum (ER)-shaping atlastin proteins (ATLs) have been demonstrated to play a functional role during flavivirus replication in mammalian cells. For dengue virus (DENV), atlastin is required in the formation of the replication organelles and RNA replication, virion ...
Keywords: , , , , , , ,

Analysis of Aedes aegypti microRNAs in response to Wolbachia wAlbB infection and their potential role in mosquito longevity

C. Bishop, M. Hussain, L. E. Hugo and S. Asgari,  Scientific Reports,  12:15245. 2022.
The mosquito Aedes aegypti is the primary vector of a range of medically important viruses including dengue, Zika, West Nile, yellow fever, and chikungunya viruses. The endosymbiotic bacterium Wolbachia pipientis wAlbB strain is a promising biocontrol agent for blocking viral ...
Keywords: , , , , , , ,

Modified mosquito releases to fight dengue fever, chikungunya or yellow fever

Sewell, Tammy,  OICANADIAN,  2022.
To date, only one technique based on genetically modified mosquitoes has been developed at an operational level, it is the RIDL technique (release of insects carrying a dominant lethal gene, or release of insects carrying a dominant lethality gene). Male mosquitoes which, unlike ...
Keywords: , , , , , , ,

Call for public consultation ̶ Development of Target Product Profiles (TPPs) for Wolbachia infected Aedes aegypti population replacement intervention

World Health Organization,  WHO,  2022.
WHO aims to reduce the global burden of dengue by 25% by 2030. To reach this goal, it is imperative to provide control programmes with sustainable vector control tools. Wolbachia, a symbiotic bacterium that occurs naturally in many insects, has been successfully transferred into ...
Keywords: , , , , , , ,

World Mosquito Day: Can genetic modification techniques quash the menace?

CNBCTV18,  CNBC TV18,  2022.
Genetically modified (GM) mosquitoes are prepared in labs and are supposed to fight the Aedes aegypti mosquitoes which spread viruses including dengue, Zika, and chikungunya. Billions have apparently been successfully released in the US, Brazil, the Cayman Islands, Panama, and ...
Keywords: , , , , , , ,

A multiplexed, confinable CRISPR/Cas9 gene drive propagates in caged Aedes aegypti populations

M. A. E. Anderson, E. Gonzalez, M. P. Edgington, J. X. D. Ang, D.-K. Purusothaman, L. Shackleford, K. Nevard, S. A. N. Verkuijl, T. Harvey-Samuel, P. T. Leftwich, K. Esvelt and L. Alphey,  bioRxiv,  2022.08.12.503466. 2022.
Here, we test the regulatory sequences from the Ae. aegypti benign gonial cell neoplasm (bgcn) homolog to express Cas9 in the germline to find an expression timing more conducive to homing. We also created a separate multiplexing (targeting multiple different sites within the ...
Keywords: , , , , , , ,

Changing mosquito genes, spreading bacteria: Science sees success vs dengue

C. E. Baclig,  INQUIRER.NET,  2022.
Wolbachia, according to WMP, are extremely common bacteria that occur naturally in 50 percent of insect species, including mosquitoes, fruit flies, moths, dragonflies, and butterflies. Aedes aegypti or dengue-carrying mosquitoes, however, do not normally carry Wolbachia. Studies ...
Keywords: , , , , , , ,

Aedes aegypti and Ae. albopictus microbiome/virome: new strategies for controlling arboviral transmission?

M. Gómez, D. Martinez, M. Muñoz and J. D. Ramírez,  Parasites and Vectors,  15:287. 2022.
Aedes aegypti and Aedes albopictus are the main vectors of highly pathogenic viruses for humans, such as dengue (DENV), chikungunya (CHIKV), and Zika (ZIKV), which cause febrile, hemorrhagic, and neurological diseases and remain a major threat to global public health. The high ...
Keywords: , , , , , , ,

The AalNix3&4 isoform is required and sufficient to convert Aedes albopictus females into males

Y. Zhao, B. Jin, P. Liu, X. Xiao, L. Cai, Z. Xie, L. Kong, T. Liu, W. Yang, Y. Wu, J. Gu, Z. Tu, A. A. James and X.-G. Chen,  PLOS Genetics,  18:e1010280. 2022.
Author summary Nix serves as a conserved male-determining factor in the two most important mosquito arboviral vectors, Ae. aegypti and Ae. albopictus. AaeNix alone can convert Ae. aegypti females into fertile but flightless males. AalNix has four alternative splice isoforms ...
Keywords: , , , , , , ,

Establishment of Wolbachia infection in Aedes aegypti from Pakistan via embryonic microinjection and semi-field evaluation of general fitness of resultant mosquito population

M. S. Sarwar, N. Jahan, A. Ali, H. K. Yousaf and I. Munzoor,  Parasites and Vectors,  15:191. 2022.
BACKGROUND: Dengue is a mosquito-borne viral disease that is mainly spread by Aedes aegypti. It is prevalent on five continents, predominantly in tropical and sub-tropical zones across the world. Wolbachia bacteria have been extensively used in vector control strategies ...
Keywords: , , , , , , ,

Reply to: Assessing the efficiency of Verily’s automated process for production and release of male Wolbachia-infected mosquitoes

J. E. Crawford, K. C. Hopkins, A. Buchman, T. Zha, P. Howell, E. Kakani, J. R. Ohm, N. Snoad, L. Upson, J. Holeman, P. Massaro, S. L. Dobson, F. S. Mulligan and B. J. White,  Nature Biotechnology,  2022.
We appreciate the comments from Bouyer et al. under their mandate as a United Nations agency program (‘to promote the safe and appropriate use of nuclear techniques and related technologies in food and agriculture’) on our paper1 . The centuries-old fight against ...
Keywords: , , , , , , ,

Assessing the efficiency of Verily’s automated process for production and release of male Wolbachia-infected mosquitoes

J. Bouyer, H. Maiga and M. J. B. Vreysen,  Nature Biotechnology,  2022.
A paper by Crawford et al.1 titled ‘Efficient production of male Wolbachia-infected Aedes aegypti mosquitoes enables large-scale suppression of wild populations’ reports a mosquito control suppression trial carried out from2017 to 2018 in Fresco Country, California, USA1 . ...
Keywords: , , , , , , ,

Elimination of a closed population of the yellow fever mosquito, Aedes aegypti, through releases of self-limiting male mosquitoes

P. B. Patil, S. K. Dasgupta, K. Gorman, A. Pickl-Herk, M. Puinean, A. McKemey, B. Char, U. B. Zehr and S. R. Barwale,  PLOS Neglected Tropical Diseases,  16:e0010315. 2022.
Author summary Aedes aegypti L. species is the primary vector responsible for transmission of the dengue virus worldwide including chikungunya, yellow fever and Zika virus. The experiment presented in the manuscript represents a study undertaken to demonstrate suppression of the ...
Keywords: , , , , , , ,

Mosquitoes Genetically Modified to Stop Disease Pass Early Test

L. Rapaport,  WebMD,  2022.
Genetically modified mosquitoes released in the U.S. appear to have passed an early test that suggests they might one day help reduce the population of insects that transmit infectious diseases. As part of the test, scientists released nearly 5 million genetically engineered ...
Keywords: , , , , , , ,

Setting the world’s deadliest animal to self-destruct

A. Ossola,  QUARTZ,  2022.
The mosquitoes are coming - and the, hopefully, they're going. This wee, British biotech company Oxitec plans to kick off a months-long experiment in which it will release billions of Aedes aegypti mosquitoes in California and Florida. But these aren't just any mosquitoes - ...
Keywords: , , , , , , ,

Genetically Modified Mosquitoes May Protect The World From Disease

J. R. Learn,  DISCOVER,  2022.
Forget lions, hippos or venomous spiders. Aedes aegypti mosquitoes may be among the deadliest wildlife in the world. Their bite is relatively harmless in normal circumstances. But many of these mosquitoes carry diseases they transmit from the blood of one host to another, ...
Keywords: , , , , , , ,

Engineering a self-eliminating transgene in the yellow fever mosquito, Aedes aegypti

K. Chae, C. Dawson, C. Valentin, B. Contreras, J. Zapletal, K. M. Myles and Z. N. Adelman,  PNAS Nexus,  2022.
Promising genetics-based approaches are being developed to reduce or prevent the transmission of mosquito-vectored diseases. Less clear is how such transgenes can be removed from the environment, a concern that is particularly relevant for highly invasive gene drive transgenes. ...
Keywords: , , , , , , ,

Pilot trial using mass field-releases of sterile males produced with the incompatible and sterile insect techniques as part of integrated Aedes aegypti control in Mexico

A. Martín-Park, A. Che-Mendoza, Y. Contreras-Perera, S. Pérez-Carrillo, H. Puerta-Guardo, J. Villegas-Chim, G. Guillermo-May, A. Medina-Barreiro, H. Delfín-González, R. Méndez-Vales, S. Vázquez-Narvaez, J. Palacio-Vargas, F. Correa-Morales, G. Ayora-Tal,  PLoS Negl Trop Dis,  16:e0010324. 2022.
We implemented a controlled before-and-after quasi-experimental study in two suburban localities of Yucatan (Mexico): San Pedro Chimay (SPC), which received IIT-SIT, and San Antonio Tahdzibichén used as control. Release of wAlbB Ae. aegypti males at SPC extended for 6 months ...
Keywords: , , , , , , ,

A metapopulation approach to identify targets for Wolbachia-based dengue control

A. Reyna-Lara, D. Soriano-Paños, J. H. Arias-Castro, H. J. Martínez and J. Gómez-Gardeñes,  Chaos,  32:041105. 2022.
Over the last decade, the release of Wolbachia-infected Aedes aegypti into the natural habitat of this mosquito species has become the most sustainable and long-lasting technique to prevent and control vector-borne diseases, such as dengue, zika, or chikungunya. However, the ...
Keywords: , , , , , , ,

Environmental factors influence the local establishment of Wolbachia in Aedes aegypti mosquitoes in two small communities in central Vietnam [version 2]

N. T. Hien, D. D. Anh, N. H. Le, N. T. Yen, T. V. Phong, V. S. Nam, T. N. Duong, N. B. Nguyen, D. T. T. Huong, L. Q. Hung, C. N. T. Trinh, N. V. Hoang, V. Q. Mai, L. T. Nghia, N. T. Dong, L. H. Tho, S. Kutcher, T. P. Hurst, J. L. Montgomery, M. Woolfit, E,  Gates Open Research,  5:147. 2022.
Background: The wMel strain of Wolbachia has been successfully introduced into Aedes aegypti mosquitoes and subsequently shown to reduce transmission of dengue and other pathogens, under both laboratory and field conditions. Here we describe the entomological outcomes of wMel ...
Keywords: , , , , , , ,

Potential Adverse Effects of GE Mosquitoes Unknown

B. Giuffre,  The Epoch Times,  2022.
“Safe and sustainable.” That’s what Oxitec, a British biological pest control company, calls its genetically modified (GM) or genetically engineered (GE) mosquito pesticide product. The company claims its product is nontoxic to humans and animals and won’t harm beneficial ...
Keywords: , , , , , , ,

Comparison of Ground Release and Drone-Mediated Aerial Release of Aedes aegypti Sterile Males in Southern Mexico: Efficacy and Challenges

C. F. Marina, P. Liedo, J. G. Bond, A. R. Osorio, J. Valle, R. Angulo-Kladt, Y. Gómez-Simuta, I. Fernández-Salas, A. Dor and T. Williams,  Insects,  13. 2022.
Sterile males of Aedes aegypti were released once a week for 8 weeks to evaluate the dispersal efficiency of ground and aerial drone release methods in a rural village of 26 Ha in southern Mexico. Indoor and outdoor BG-Sentinel traps were placed in 13–16 houses distributed ...
Keywords: , , , , , , ,

Genetic Stability and Fitness of Aedes aegypti Red-Eye Genetic Sexing Strains With Pakistani Genomic Background for Sterile Insect Technique Applications

M. Misbah-ul-Haq, D. O. Carvalho, L. D. de la Fuente, A. A. Augustinos and K. Bourtzis,  Frontiers in Bioengineering and Biotechnology,  10. 2022.
The mosquito species Aedes aegypti is the primary transmitter of viruses that cause endemic diseases like dengue in Pakistan. It is also a cause of other vector-borne diseases like yellow fever, Zika fever, and chikungunya, which significantly impact human health worldwide. In ...
Keywords: , , , , , , ,

Combining two Genetic Sexing Strains allows sorting of non-transgenic males for Aedes genetic control

C. Lutrat, M. Burckbuchler, R. P. Olmo, R. Beugnon, A. Fontaine, T. Baldet, J. Bouyer and E. Marois,  bioRxiv,  2022.03.11.483912. 2022.
Chemical control of the mosquito vectors Aedes albopictus and Aedes aegypti is costly, unsustainable, and increasingly ineffective due to the spread of insecticide resistance. The Sterile Insect Technique is an autocidal control tactic that represents a valuable alternative but ...
Keywords: , , , , , , ,

GMO mosquitoes set for release in California to quell disease

M. Renda,  Courthouse News Service,  2022.
The U.S. Environmental Protection Agency approved the experimental use of genetically engineered mosquitoes in California and Florida to reduce the populations of invasive mosquitoes that carry a host of infectious diseases like Zika and dengue fever. “With mosquito and ...
Keywords: , , , , , , ,

EVITA Dengue: a cluster-randomized controlled trial to EValuate the efficacy of Wolbachia-InfecTed Aedes aegypti mosquitoes in reducing the incidence of Arboviral infection in Brazil

M. H. Collins, G. E. Potter, M. D. T. Hitchings, E. Butler, M. Wiles, J. K. Kennedy, S. B. Pinto, A. B. M. Teixeira, A. Casanovas-Massana, N. G. Rouphael, G. A. Deye, C. P. Simmons, L. A. Moreira, M. L. Nogueira, D. A. T. Cummings, A. I. Ko, M. M. Teixeir,  Trials,  23:185. 2022.
BACKGROUND: Arboviruses transmitted by Aedes aegypti including dengue, Zika, and chikungunya are a major global health problem, with over 2.5 billion at risk for dengue alone. There are no licensed antivirals for these infections, and safe and effective vaccines are not yet ...
Keywords: , , , , , , ,

Adult mosquito predation and potential impact on the sterile insect technique

N. S. Bimbilé Somda, H. Maïga, W. Mamai, T. Bakhoum, T. Wallner, S. B. Poda, H. Yamada and J. Bouyer,  Scientific Reports,  12:2561. 2022.
The sterile insect technique is a promising environmentally friendly method for mosquito control. This technique involves releasing laboratory-produced sterile males into a target field site, and its effectiveness may be affected by the extent of adult mosquito predation. Sterile ...
Keywords: , , , , , , ,

Assessing Aedes aegypti candidate genes during viral infection and Wolbachia-mediated pathogen blocking

L. T. Sigle, M. Jones, M. Novelo, S. A. Ford, N. Urakova, K. Lymperopoulos, R. T. Sayre, Z. Xi, J. L. Rasgon and E. A. McGraw,  Insect Molecular Biology,  2022.
Abstract One approach to control dengue virus transmission is the symbiont Wolbachia, that limits viral infection in mosquitoes. Despite plans for its widespread use in Aedes aegypti, Wolbachia's mode of action remains poorly understood. Many studies suggest that the mechanism is ...
Keywords: , , , , , , ,

A flavivirus-inducible gene expression system that modulates broad-spectrum antiviral activity against dengue and Zika viruses

S.-C. Weng, Y.-X. Zhou and S.-H. Shiao,  Insect Biochemistry and Molecular Biology,  142:103723. 2022.
Incidence of dengue virus (DENV) and Zika virus (ZIKV), two mosquito-borne flaviviruses, is increasing in large parts of the world. Vaccination and medication for these diseases are unsatisfactory. Here, we developed a novel antiviral approach, using a virus-inducible gene ...
Keywords: , , , , , , ,

Could Sterile Aedes albopictus Male Releases Interfere with Aedes aegypti Population in Reunion Island?

H. F. Andrianjakarivony, D. Damiens, L. Marquereau, B. Gaudillat, N. Habchi-Hanriot and L.-C. Gouagna,  Insects,  13. 2022.
In Reunion Island, the feasibility of an Aedes albopictus control program using the Sterile Insect Technique (SIT) is studied. Because, in some regions, Ae. albopictus is living in sympatry with Aedes aegypti, the impact of releasing millions of sterile male Ae. albopictus on ...
Keywords: , , , , , , ,

Effects of Sterile Males and Fertility of Infected Mosquitoes on Mosquito-Borne Disease Dynamics

X. L. Sun, S. Q. Liu, Y. F. Lv and Y. Z. Pei,  Bulletin of Mathematical Biology,  84:33. 2022.
By studying an infection-age structured model, we consider the effects of releasing sterile males and the fertility of infected mosquitoes on the mosquito-borne diseases transmission including the extinction of mosquitoes, the elimination and persistence of diseases. Firstly, ...
Keywords: , , , , , , ,

The prince, the mayor, and the U.S. fish that ate Japan

C. Elliot,  National Geographic,  2022.
When Crown Prince Akihito visited Chicago on October 3, 1960, his sole request was to visit Shedd Aquarium. Then Mayor Richard J. Daley, an avid angler, presented the prince with a gift that he scooped with a net from one of the tanks himself: 18 bluegills, the official Illinois ...
Keywords: , , , , , , ,

Introgression of the Aedes aegypti red-eye genetic sexing strains into different genomic backgrounds for sterile insect technique applications

A. A. Augustinos , K. Nikolouli , L. D. De La Fuente , M. Misbah-Ul-Haq, D. O. Carvalho and K. Bourtzis,  Frontiers in Bioengineering and Biotechnology,  2022.
Aedes aegypti is an invasive mosquito species and major vector of human arboviruses. A wide variety of control methods have been employed to combat mosquito populations. One of them is the sterile insect technique (SIT) that has recently attracted considerable research efforts ...
Keywords: , , , , , , ,

Beyond the eye: Kynurenine pathway impairment causes midgut homeostasis dysfunction and survival and reproductive costs in blood-feeding mosquitoes

V. Bottino-Rojas, I. Ferreira, R. D. Nunes, X. Feng, T. B. Pham, A. Kelsey, R. Carballar-Lejarazú, V. Gantz, P. L. Oliveira and A. A. James,  Insect Biochemistry and Molecular Biology,  103720. 2022.
Insect ommochrome biosynthesis pathways metabolize tryptophan to generate eye-color pigments and naturally occurring alleles of pathway genes are useful phenotypic markers in transgenesis studies. Pleiotropic effects of mutations in some genes exert a load on both survival and ...
Keywords: , , , , , , ,

Perspectives into Genetic Manipulations for Control of Dengue Vector (Aedes aegypti Linnaeus, 1762) with Reference to Progress in Indian Experiments

R. Chatterjee, S. Bhattacharya and B. K. Tyagi,  Genetically Modified and other Innovative Vector Control Technologies,  2021.