Keywords: aneuploidy

Selfish centromeres and the wastefulness of human reproduction

L. D. Hurst,  PLOS Biology,  20:e3001671. 2022.
Many human embryos die in utero owing to an excess or deficit of chromosomes, a phenomenon known as aneuploidy; this is largely a consequence of nondisjunction during maternal meiosis I. Asymmetries of this division render it vulnerable to selfish centromeres that promote their ...
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