Keywords: antiviral effector

Engineered Antiviral Sensor Targets Infected Mosquitoes

Elena Dalla Benetta, Adam J. López-Denman, Hsing-Han Li, Reem A. Masri, Daniel J. Brogan, Michelle Bui, Ting Yang, Ming Li, Michael Dunn, Melissa J. Klein, Sarah Jackson, Kyle Catalan, Kim R. Blasdell, Priscilla Tng, Igor Antoshechkin, Luke S. Alphey, Pra,  The CRISPR Journal,  6:543-556. 2024.
Escalating vector disease burdens pose significant global health risks, as such innovative tools for targeting mosquitoes are critical. CRISPR-Cas technologies have played a crucial role in developing powerful tools for genome manipulation in various eukaryotic organisms. ...
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Current Effector and Gene-Drive Developments to Engineer Arbovirus-Resistant Aedes aegypti (Diptera: Culicidae) for a Sustainable Population Replacement Strategy in the Field

W. R. Reid, K. E. Olson and A. W. E. Franz,  J Med Entomol,  2021.
Conventional mosquito control efforts based on insecticide treatments and/or the use of bednets and window curtains are currently insufficient to reduce arbovirus prevalence in affected regions. Novel, genetic strategies that are being developed involve the genetic manipulation ...
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