Keywords: antiviral effector
Engineered Antiviral Sensor Targets Infected MosquitoesElena Dalla Benetta, Adam J. López-Denman, Hsing-Han Li, Reem A. Masri, Daniel J. Brogan, Michelle Bui, Ting Yang, Ming Li, Michael Dunn, Melissa J. Klein, Sarah Jackson, Kyle Catalan, Kim R. Blasdell, Priscilla Tng, Igor Antoshechkin, Luke S. Alphey, Pra, The CRISPR Journal, 6:543-556. 2024.Escalating vector disease burdens pose significant global health risks, as such innovative tools for targeting mosquitoes are critical. CRISPR-Cas technologies have played a crucial role in developing powerful tools for genome manipulation in various eukaryotic organisms. ... Keywords: Aedes, aegypti, antiviral effector, arbovirus, gene drive synthetic, mosquito, population replacement, review |
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Current Effector and Gene-Drive Developments to Engineer Arbovirus-Resistant Aedes aegypti (Diptera: Culicidae) for a Sustainable Population Replacement Strategy in the FieldW. R. Reid, K. E. Olson and A. W. E. Franz, J Med Entomol, 2021.Conventional mosquito control efforts based on insecticide treatments and/or the use of bednets and window curtains are currently insufficient to reduce arbovirus prevalence in affected regions. Novel, genetic strategies that are being developed involve the genetic manipulation ... Keywords: Aedes, aegypti, antiviral effector, arbovirus, gene drive synthetic, mosquito, population replacement, review |
Contact
David O’Brochta
Foundation for the
National Institutes of Health
geneconvenevi@fnih.org
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