Keywords: bioethics

Gene drive technologies: navigating the ethical landscape

N. d. Graeff,  Utrecht University,  2022.
Gene drives are technologies that modify a particular genetic element in animals or insects so that this genetic element does not follow the typical rules of heredity, and is passed onto future generations with an increased likelihood. Gene drive technologies could be used to ...
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Ethics of gene drive mosquitoes for malaria elimination

A. J. Roberts,  McMaster University,  2022.
This thesis is concerned with presenting analyses regarding key ethical issues regarding and arising from the development and potential use of gene drive modified mosquitoes for the purpose of malaria elimination. Each of the chapters constituting this thesis offers a rigorously ...
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Gene Editing in the Wild: Shaping Decisions through Broad Public Deliberation

M. K. Gusmano, G. E. Kaebnick, K. J. Maschke, C. P. Neuhaus and B. C. Wills,  The Hastings Center Report,  51. 2021.
The essays in this special report grew out of a project funded by the National Science Foundation (with NSF award number 1827935). Gregory E. Kaebnick and Michael K. Gusmano were co-principal investigators on the project, and Karen J. Maschke and Carolyn P. Neuhaus were ...
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Deficits of Public Deliberation in U.S. Oversight for Gene Edited Organisms

J. Kuzma,  Hastings Center Report,  51 Suppl 2:S25-s33. 2021.
Environmental releases of gene edited (GEdOs) and gene drive organisms (GDOs) will likely occur under conditions of high uncertainty and in complex socioecological systems. Therefore, public deliberation is especially important to account for diverse interpretations of safety, ...
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Public Deliberation about Gene Editing in the Wild

M. K. Gusmano, G. E. Kaebnick, K. J. Maschke, C. P. Neuhaus and B. C. Wills,  Hastings Center Report,  51 Suppl 2:S2-s10. 2021.
Genetic editing technologies have long been used to modify domesticated nonhuman animals and plants. Recently, attention and funding have also been directed toward projects for modifying nonhuman organisms in the shared environment-that is, in the "wild." Interest in gene editing ...
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Empowering Indigenous Knowledge in Deliberations on Gene Editing in the Wild

R. Taitingfong and A. Ullah,  Hastings Center Report,  51 Suppl 2:S74-s84. 2021.
Proposals to release genetically engineered organisms in the wild raise complex ethical issues related to their safe and equitable implementation. While there is broad agreement that community and public engagement is vital to decision-making in this context, more discussion is ...
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The Decision Phases Framework for Public Engagement: Engaging Stakeholders about Gene Editing in the Wild

S. K. Barnhill-Dilling, A. Kokotovich and J. A. Delborne,  Hastings Center Report,  51 Suppl 2:S48-s61. 2021.
Some experts and advocates propose environmental biotechnologies such as genetic engineering, gene drive systems, and synthetic biology as potential solutions to accelerating rates of species loss. While these tools may offer hope for a seemingly intractable problem, they also ...
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Bioethical issues in genome editing by CRISPR-Cas9 technology

F. B. Ayanoglu, A. E. Elcin and Y. M. Elcin,  Turkish Journal of Biology,  44:110-120. 2020.
Genome editing technologies have led to fundamental changes in genetic science. Among them, CRISPR-Cas9 technology particularly stands out due to its advantages such as easy handling, high accuracy, and low cost. It has made a quick introduction in fields related to humans, ...
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CRISPR-Cas9. The greatest advancement in genetic edition techniques requires an ethical reflection

Gomez-Tatay, LA, J.,  Cuadernos De Bioetica,  30:171-185. 2019.
The adaptation of the CRISPR system as a genetic editing tool has led to a revolution in many fields of application, as this technique is considerably faster, easier to perform and more efficient than predecessor techniques. However, some of these applications raise objective ...
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