Keywords: biotechnology

Gene drive technologies: navigating the ethical landscape

N. d. Graeff,  Utrecht University,  2022.
Gene drives are technologies that modify a particular genetic element in animals or insects so that this genetic element does not follow the typical rules of heredity, and is passed onto future generations with an increased likelihood. Gene drive technologies could be used to ...
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Economic issues to consider for gene drives

Mitchell, PDB, Z.; McRoberts, N.,  Journal of Responsible Innovation,  5:S180-S202. 2018.
We examine four economic issues regarding gene drive applications made possible by gene editing technologies. First, whether gene drives are self-sustaining or self-limiting will largely determine which types of organizations have incentives to develop and deploy gene drives and ...
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Gene drive inhibition by the anti-CRISPR proteins AcrIIA2 and AcrIIA4 in Saccharomyces cerevisiae

Basgall, EMG, S. C.; Goeckel, M. E.; Giersch, R. M.; Roggenkamp, E.; Schrock, M. N.; Halloran, M.; Finnigan, G. C.,  Microbiology-Sgm,  164:464-474. 2018.
Given the widespread use and application of the clustered regularly interspaced short palindromic repeats (CRISPR)/Cas gene editing system across many fields, a major focus has been the development, engineering and discovery of molecular means to precisely control and regulate ...
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A bigger toolbox: Biotechnology in biodiversity conservation

R. T. Corlett,  Trends in Biotechnology,  35:55-65. 2017.
Conservation biology needs a bigger toolbox to meet unprecedented challenges. Genomics, fueled by declining sequencing costs, offers novel tools with increased precision for genetic questions previously answered with a few molecular markers, as well as completely new ...
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