
Keywords: Candida albicans
![]() |
A CRISPR–Cas9-based gene drive platform for genetic interaction analysis in Candida albicansShapiro, RSC, Alejandro; Porter, Caroline B. M.; Hamblin, Meagan; Kaas, Christian S.; DiCarlo, James E.; Zeng, Guisheng; Xu, Xiaoli; Revtovich, Alexey V.; Kirienko, Natalia V.; Wang, Yue; Church, George M.; Collins, James J., Nature Microbiology, 3:73-82. 2018.![]() Candida albicans is the leading cause of fungal infections; yet, complex genetic interaction analysis remains cumbersome in this diploid pathogen. Here, we developed a CRISPR–Cas9-based ‘gene drive array’ platform to facilitate efficient genetic analysis in C. albicans. In ... Keywords: Candida albicans, gene drive synthetic, plants, synthetic homing drive |

Contact
David O’Brochta
Foundation for the
National Institutes of Health
geneconvenevi@fnih.org
RSS