Keywords: cattle

Unravelling transmission ratio distortion across the bovine genome: identification of candidate regions for reproduction defects

S. Id-Lahoucine, J. Casellas, A. Suárez-Vega, P. A. S. Fonseca, F. S. Schenkel, M. Sargolzaei and A. Cánovas,  BMC Genomics,  24:383. 2023.
Our results revealed the importance of implementing different TRD parameterizations to capture all types of distortions and to determine the corresponding inheritance pattern. Novel candidate genomic regions containing lethal alleles and genes with functional and biological ...
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Meet Cosmo, the gene-edited Crispr calf

S. D. McClain,  Capital Press,  2020.
Cosmo was the grand finale of a series of experiments to create a line of genome-edited cattle tailored for the beef industry. He was designed to produce 75% male offspring.
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The future of beef might be a sausage fest

N. Johnson,  grist,  2020.
N. Johnson. (2020) grist. A media report on the creation of a cow with a sex ratio altering genetic change expected to lead to 3/4 of the cow's offspring being males. This type of sex ratio distortion results in gene drive and is also being considered to help control populations ...
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Meet Cosmo the Frankenbull: Scientists genetically engineer a bull calf so that 75 per cent of its offspring will be male

J. Pinkstone,  Daily Mail,  2020.
J. Pinkstone (2020). Daily Mail. A media report on the creation of a cow with a sex ratio altering genetic change expected to lead to 3/4 of the cow's offspring being males. This type of sex ratio distortion results in gene drive and is also being considered to help control ...
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A Crispr calf is born. It’s definitely a boy

M. Molteni,  WIRED,  2020.
M. Molteni (2020). Wired. UC Davis scientists spent years editing a sex-determining gene into bovine embryos. In April, Cosmo arrived—and his DNA reveals how far the field has to go. This type of sex ratio distortion results in gene drive and is also being considered to help ...
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Meet the first genetically modified bull. Why did scientists change it

J. Kessler,  Free News,  2020.
J. Kessler (2020). Free News. UC Davis scientists have successfully introduced a bovine embryo, or the bovine SRY gene, which is responsible for the development of the male. This is the first demonstration of targeted gene insertion for large DNA sequences through embryo-mediated ...
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Scientists use CRISPR technology to insert sex-determining gene

A. Quinton,  Phys Org,  2020.
A. Quinton (2020). Phys Org. Scientists at the University of California, Davis, have successfully produced a bull calf, named Cosmo, who was genome-edited as an embryo so that he'll produce more male offspring. The research was presented in a poster on July 23 at the American ...
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