
Keywords: centromere
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Parallel pathways for recruiting effector proteins determine centromere drive and suppressionT. Kumon, J. Ma, R. B. Akins, D. Stefanik, C. E. Nordgren, J. Kim, M. T. Levine and M. A. Lampson, Cell, 2021.![]() Selfish centromere DNA sequences bias their transmission to the egg in female meiosis. Evolutionary theory suggests that centromere proteins evolve to suppress costs of this "centromere drive." In hybrid mouse models with genetically different maternal and paternal centromeres, ... Keywords: Aegilops speltoides, asymmetric spindle, b chromosomes, centromere, chromosome drive, chromosome nondisjunction, gene drive natural |
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Sequence of the supernumerary B chromosome of maize provides insight into its drive mechanism and evolutionN. Blavet, H. Yang, H. Su, P. Solanský, R. N. Douglas, M. Karafiátová, L. Šimková, J. Zhang, Y. Liu, J. Hou, X. Shi, C. Chen, M. El-Walid, M. E. McCaw, P. S. Albert, Z. Gao, C. Zhao, G. Ben-Zvi, L. Glick, G. Kol, J. Shi, J. Vrána, H. Šimková, J. C. Lamb,, Proceedings of the National Academy of Sciences, 118:e2104254118. 2021.![]() B chromosomes are nonvital chromosomes found in thousands of plants and animals that persist through various drive mechanisms. The drive mechanism of the maize B chromosome consists of mitotic nondisjunction at the second pollen division to produce two unequal sperm and then the ... Keywords: Aegilops speltoides, asymmetric spindle, b chromosomes, centromere, chromosome drive, chromosome nondisjunction, gene drive natural |
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Nondisjunction and unequal spindle organization accompany the drive of Aegilops speltoides B chromosomesD. Wu, A. Ruban, J. Fuchs, J. Macas, P. Novák, M. Vaio, Y. Zhou and A. Houben, New Phytologist, 223:1340-1352. 2021.![]() B chromosomes (Bs) are supernumerary chromosomes, which are often preferentially inherited. When transmission rates of chromosomes are higher than 0.5, not obeying the Mendelian law of equal segregation, the resulting transmission advantage is collectively referred to as ... Keywords: Aegilops speltoides, asymmetric spindle, b chromosomes, centromere, chromosome drive, chromosome nondisjunction, gene drive natural |

Contact
David O’Brochta
Foundation for the
National Institutes of Health
geneconvenevi@fnih.org
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