
Keywords: chemical control
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Maintenance management and eradication of established aquatic invadersD. Simberloff, Hydrobiologia, 22. 2020.![]() The rapid development of technologies based on genetics has engendered excitement about possibly eradicating or controlling terrestrial invaders, and such technologies may also prove useful for certain aquatic invaders. Methods of particular interest, alone or in various ... Keywords: chemical control, control, drosophila, gene drive synthetic, melanogaster, remediation, reversal, Rippase, RU486, synthetic homing drive |
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Chemical controllable gene drive in DrosophilaD. Chae, J. Lee, N. Lee, K. Park, S. J. Moon and H. H. Kim, ACS Synthetic Biology, in press. 2020.![]() Here, we report a chemical-induced control of gene drive. We prepared a CRISPR-based gene drive system that can be removed by a site-specific recombinase, Rippase, the expression of which is induced by the chemical RU486 in fruit flies. Exposure of fruit flies to RU486 resulted ... Keywords: chemical control, control, drosophila, gene drive synthetic, melanogaster, remediation, reversal, Rippase, RU486, synthetic homing drive |

Contact
David O’Brochta
Foundation for the
National Institutes of Health
geneconvenevi@fnih.org
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