
Keywords: complex
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Controlling invasive rodents via synthetic gene drive and the role of polyandryManser, AC, S. J.; Sutter, A.; Blondel, D. V.; Serr, M.; Godwin, J.; Price, T. A. R., Proceedings of the Royal Society B-Biological Sciences, 286:9. 2019.![]() House mice are a major ecosystem pest, particularly threatening island ecosystems as a non-native invasive species. Rapid advances in synthetic biology offer new avenues to control pest species for biodiversity conservation. Recently, a synthetic sperm-killing gene drive ... Keywords: complex, invadability, Mathematical model, meiotic drive, Mendelian segregation, rareness advantage, segregation distortion, Shaw–Mohler equation |
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A synthetic maternal-effect selfish genetic element drives population replacement in DrosophilaChen, CHH, H. X.; Ward, C. M.; Su, J. T.; Schaeffer, L. V.; Guo, M.; Hay, B. A., Science, 316:597-600. 2007.![]() One proposed strategy for controlling the transmission of insect-borne pathogens uses a drive mechanism to ensure the rapid spread of transgenes conferring disease refractoriness throughout wild populations. Here, we report the creation of maternal-effect selfish genetic elements ... Keywords: complex, invadability, Mathematical model, meiotic drive, Mendelian segregation, rareness advantage, segregation distortion, Shaw–Mohler equation |
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Competition at the Mouse t Complex: Rare Alleles Are Inherently Favoredvan Boven, MW, Franz J., Theoretical Population Biology, 60:343-358. 2001.![]() We investigate the competition between alleles at a segregation distorter locus. The focus is on the invasion prospects of rare mutant distorter alleles in a population in which a wildtype and a resident distorter allele are present. The parameters are chosen to reflect the ... Keywords: complex, invadability, Mathematical model, meiotic drive, Mendelian segregation, rareness advantage, segregation distortion, Shaw–Mohler equation |

Contact
David O’Brochta
Foundation for the
National Institutes of Health
geneconvenevi@fnih.org
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