Keywords: contromere drive
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Selfish centromeres and the wastefulness of human reproductionL. D. Hurst, PLOS Biology, 20:e3001671. 2022.
Many human embryos die in utero owing to an excess or deficit of chromosomes, a phenomenon known as aneuploidy; this is largely a consequence of nondisjunction during maternal meiosis I. Asymmetries of this division render it vulnerable to selfish centromeres that promote their ... |
