Keywords: demographic parameters

Demographic feedbacks can hamper the spatial spread of a gene drive

L. Girardin and F. Débarre,  Journal of Mathematical Biology,  83:67. 2021.
This paper is concerned with a reaction–diffusion system modeling the fixation and the invasion in a population of a gene drive (an allele biasing inheritance, increasing its own transmission to offspring). In our model, the gene drive has a negative effect on the fitness of ...
Keywords: , , , , , , , ,

Demographic feedbacks can hamper the spatial spread of a gene drive

L. Girardin and F. Débarre,  arXiv,  2021.
Our results indicate that taking into account the interplay between population dynamics and population genetics might actually be crucial, as it can effectively reverse the direction of the invasion and lead to failure. Our findings can be extended to other bistable systems, such ...
Keywords: , , , , , , , ,