
Keywords: disease
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Engineered resistance to Zika virus in transgenic Aedes aegypti expressing a polycistronic cluster of synthetic small RNAsBuchman, AG, S.; Li, M.; Antoshechkin, I.; Li, H. H.; Wang, H. W.; Chen, C. H.; Klein, M. J.; Duchemin, J. B.; Paradkar, P. N.; Akbari, O. S., Proceedings of the National Academy of Sciences of the United States of America, 116:3656-3661. 2019.![]() Recent Zika virus (ZIKV) outbreaks have highlighted the necessity for development of novel vector control strategies to combat arboviral transmission, including genetic versions of the sterile insect technique, artificial infection with Wolbachia to reduce population size and/or ... Keywords: Anopheles, Anopheles gambiae, artemisinin, disease, dynamics, epidemiology, gene drive models, gene drive natural, gene drive synthetic, homing endonuceases, insecticide resistance, insects, malaria, malaria control, spatial modelling, spatial spread, system, vector-borne disease, vectors |
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Modelling the spatial spread of a homing endonuclease gene in a mosquito populationNorth, AB, A.; Godfray, H. C. J., Journal of Applied Ecology, 50:1216-1225. 2013.![]() Homing endonuclease genes (HEGs) exist naturally in many single-celled organisms and can show extremely strong genetic drive allowing them to spread through populations into which they are introduced. They are being investigated as tools to manipulate the populations of important ... Keywords: Anopheles, Anopheles gambiae, artemisinin, disease, dynamics, epidemiology, gene drive models, gene drive natural, gene drive synthetic, homing endonuceases, insecticide resistance, insects, malaria, malaria control, spatial modelling, spatial spread, system, vector-borne disease, vectors |

Contact
David O’Brochta
Foundation for the
National Institutes of Health
geneconvenevi@fnih.org
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