Keywords: DNA

The association between mitochondrial genetic variation and reduced colony fitness in an invasive wasp

J. Dobelmann, A. Alexander, J. W. Baty, N. J. Gemmell, M. A. M. Gruber, O. Quinn, T. Wenseleers and P. J. Lester,  Molecular Ecology,  28:3324-3338. 2019.
Despite the mitochondrion's long-recognized role in energy production, mitochondrial DNA (mtDNA) variation commonly found in natural populations was assumed to be effectively neutral. However, variation in mtDNA has now been increasingly linked to phenotypic variation in life ...
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Rapid comeback of males: evolution of male-killer suppression in a green lacewing population

Hayashi, MN, M.; Kageyama, D.,  Proceedings of the Royal Society B-Biological Sciences,  285:6. 2018.
Evolutionary theory predicts that the spread of cytoplasmic sex ratio distorters leads to the evolution of host nuclear suppressors, although there are extremely few empirical observations of this phenomenon. Here, we demonstrate that a nuclear suppressor of a cytoplasmic male ...
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A bigger toolbox: Biotechnology in biodiversity conservation

R. T. Corlett,  Trends in Biotechnology,  35:55-65. 2017.
Conservation biology needs a bigger toolbox to meet unprecedented challenges. Genomics, fueled by declining sequencing costs, offers novel tools with increased precision for genetic questions previously answered with a few molecular markers, as well as completely new ...
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Rapid evolution of yeast centromeres in the absence of drive

Bensasson, DZ, M.; Burt, A.; Koufopanou, V.,  Genetics,  178:2161-2167. 2008.
To find the most rapidly evolving regions in the yeast genome we compared most of chromosome III from three closely related lineages of the wild yeast Saccharomyces paradoxits. Unexpectedly, the centromere appears to be the fastest-evolving part of the chromosome, evolving even ...
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The distribution of B chromosomes across species

Palestis, BGT, R.; Burt, A.; Jones, R. N.,  Cytogenetic and Genome Research,  106:151-158. 2004.
In this review we look at the broad picture of how B chromosomes are distributed across a wide range of species. We review recent studies of the factors associated with the presence of Bs across species, and provide new analyses with updated data and additional variables. The ...
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Homing endonuclease genes: the rise and fall and rise again of a selfish element

Burt, AK, V.,  Current Opinion in Genetics & Development,  14:609-615. 2004.
Homing endonuclease genes (HEGs) are selfish genetic elements that spread by first cleaving chromosomes that do not contain them and then getting copied across to the broken chromosome as a byproduct of the repair process. The success of this strategy will depend on the ...
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Site-specific selfish genes as tools for the control and genetic engineering of natural populations

Burt, A,  Proceedings of the Royal Society B-Biological Sciences,  270:921-928. 2003.
Site-specific selfish genes exploit host functions to copy themselves into a defined target DNA sequence, and include homing endonuclease genes, group II introns and some LINE-like transposable elements. If such genes can be engineered to target new host sequences, then they can ...
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Adaptation for horizontal transfer in a homing endonuclease

Koufopanou, VG, M. R.; Burt, A.,  Molecular Biology and Evolution,  19:239-246. 2002.
Selfish genes of no function other than self-propagation are susceptible to degeneration if they become fixed in a population. and regular transfer to new species may be the only means for their long-term persistence. To test this idea we surveyed 24 species of yeast for VDE, a ...
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Outcrossed sex allows a selfish gene to invade yeast populations

Goddard, MRG, D.; Burt, A.,  Proceedings of the Royal Society B-Biological Sciences,  268:2537-2542. 2001.
Homing endonuclease genes (HEGs) in eukaryotes are optional genes that have no obvious effect on host phenotype except for causing chromosomes not containing a cop), of the gene to be cut, thus causing them to be inherited at a greater than Mendelian rate via gene conversion. ...
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