Keywords: Drosophila melanogaster embryo lethality temperature sensitivity paralysis CRISPR/Cas9 mutagenesis

Lessons from Drosophila: Engineering Genetic Sexing Strains with Temperature-Sensitive Lethality for Sterile Insect Technique Applications

T. N. M. Nguyen, A. Choo and S. W. Baxter,  Insects,  12. 2021.
Some of the most successful Genetic Sexing Strains (GSS) reared and released for SIT control were developed for Mediterranean fruit fly (Medfly), Ceratitis capitata, and carry a temperature sensitive lethal (tsl) mutation that eliminates female but not male embryos when heat ...