
Keywords: dynamics
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A One-Sided Competition Mathematical Model for the Sterile Insect TechniqueA. Ben Dhahbi, Y. Chargui, S. M. Boulaaras and S. Ben Khalifa, Complexity, 2020:12. 2020.![]() We study a simple mathematical model describing the dynamics of a wild-type pest insects population experiencing competition from sterile insects (one-sided competition). Keywords: aides-aegypti, Anopheles gambiae, behavior, complex, dynamics, history 2000-present, malaria parasite, mosquitos, resistance, Science & Technology - Other Topics, systems, vectors |
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Detecting the population dynamics of an autosomal sex ratio distorter transgene in malaria vector mosquitoesP. Pollegioni, A. R. North, T. Persampieri, A. Bucci, R. L. Minuz, D. A. Groneberg, T. Nolan, P. A. Papathanos, A. Crisanti and R. Muller, Journal of Applied Ecology, 11. 2020.![]() A sex-distorting autosomal transgene has been developed recently in G3 mosquitoes, a laboratory strain of the malaria vectorAnopheles gambiaes.l. Following the World Health Organization guidance framework for the testing of GM mosquitoes, we assessed the dynamics of this ... Keywords: aides-aegypti, Anopheles gambiae, behavior, complex, dynamics, history 2000-present, malaria parasite, mosquitos, resistance, Science & Technology - Other Topics, systems, vectors |
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Controlling invasive rodents via synthetic gene drive and the role of polyandryManser, AC, S. J.; Sutter, A.; Blondel, D. V.; Serr, M.; Godwin, J.; Price, T. A. R., Proceedings of the Royal Society B-Biological Sciences, 286:9. 2019.![]() House mice are a major ecosystem pest, particularly threatening island ecosystems as a non-native invasive species. Rapid advances in synthetic biology offer new avenues to control pest species for biodiversity conservation. Recently, a synthetic sperm-killing gene drive ... Keywords: aides-aegypti, Anopheles gambiae, behavior, complex, dynamics, history 2000-present, malaria parasite, mosquitos, resistance, Science & Technology - Other Topics, systems, vectors |
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Sperm competition suppresses gene drive among experimentally evolving populations of house miceManser, AL, A. K.; Simmons, L. W.; Firman, R. C., Molecular Ecology, 26:5784-5792. 2017.![]() Drive genes are genetic elements that manipulate the 50% ratio of Mendelian inheritance in their own favour, allowing them to rapidly propagate through populations. The action of drive genes is often hidden, making detection and identification inherently difficult. Yet drive ... Keywords: aides-aegypti, Anopheles gambiae, behavior, complex, dynamics, history 2000-present, malaria parasite, mosquitos, resistance, Science & Technology - Other Topics, systems, vectors |
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Modelling the spatial spread of a homing endonuclease gene in a mosquito populationNorth, AB, A.; Godfray, H. C. J., Journal of Applied Ecology, 50:1216-1225. 2013.![]() Homing endonuclease genes (HEGs) exist naturally in many single-celled organisms and can show extremely strong genetic drive allowing them to spread through populations into which they are introduced. They are being investigated as tools to manipulate the populations of important ... Keywords: aides-aegypti, Anopheles gambiae, behavior, complex, dynamics, history 2000-present, malaria parasite, mosquitos, resistance, Science & Technology - Other Topics, systems, vectors |
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Analysis of the Trojan Y chromosome model for eradication of invasive species in a dendritic riverine systemJ. B. Gutierrez, M. K. Hurdal, R. D. Parshad and J. L. Teem, Journal of Mathematical Biology, 64:319-340. 2011.![]() The use of Trojan Y chromosomes has been proposed as a genetic strategy for the eradication of invasive species. The strategy is particularly relevant to invasive fish species that have XY sex determination system and are amenable to sex-reversal. In this paper we study the ... Keywords: aides-aegypti, Anopheles gambiae, behavior, complex, dynamics, history 2000-present, malaria parasite, mosquitos, resistance, Science & Technology - Other Topics, systems, vectors |
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Requirements for effective malaria control with homing endonuclease genesDeredec, AG, H. C. J.; Burt, A., Proceedings of the National Academy of Sciences of the United States of America, 108:e874-e880. 2011.![]() Malaria continues to impose a substantial burden on human health. We have previously proposed that biological approaches to control the mosquito vector of disease could be developed using homing endonuclease genes (HEGs), a class of selfish or parasitic gene that exists naturally ... Keywords: aides-aegypti, Anopheles gambiae, behavior, complex, dynamics, history 2000-present, malaria parasite, mosquitos, resistance, Science & Technology - Other Topics, systems, vectors |
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A synthetic maternal-effect selfish genetic element drives population replacement in DrosophilaChen, CHH, H. X.; Ward, C. M.; Su, J. T.; Schaeffer, L. V.; Guo, M.; Hay, B. A., Science, 316:597-600. 2007.![]() One proposed strategy for controlling the transmission of insect-borne pathogens uses a drive mechanism to ensure the rapid spread of transgenes conferring disease refractoriness throughout wild populations. Here, we report the creation of maternal-effect selfish genetic elements ... Keywords: aides-aegypti, Anopheles gambiae, behavior, complex, dynamics, history 2000-present, malaria parasite, mosquitos, resistance, Science & Technology - Other Topics, systems, vectors |

Contact
David O’Brochta
Foundation for the
National Institutes of Health
geneconvenevi@fnih.org
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