
Keywords: elegans
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A Maternal-Effect Toxin Affects Epithelial Differentiation and Tissue Mechanics in Caenorhabditis elegansC. Lehmann and C. Pohl, Frontiers in Cell and Developmental Biology, 9. 2021.![]() Selfish genetic elements that act as post-segregation distorters cause lethality in non-carrier individuals after fertilization. Two post-segregation distorters have been previously identified in Caenorhabditis elegans, the peel-1/zeel-1 and the sup-35/pha-1 elements. These ... Keywords: Caenorhabditis, elegans, gene drive natural, meiotic drive, selfish DNA, selfish genetic element, toxin antidote |
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Ubiquitous Selfish Toxin-Antidote Elements in Caenorhabditis SpeciesE. Ben-David, P. Pliota, S. A. Widen, A. Koreshova, T. Lemus-Vergara, P. Verpukhovskiy, S. Mandali, C. Braendle, A. Burga and L. Kruglyak, Current Biology, 2021.![]() Here, we report the discovery of maternal-effect TAs in both C. tropicalis and C. briggsae, two distant relatives of C. elegans. In C. tropicalis, multiple TAs combine to cause a striking degree of intraspecific incompatibility: five elements reduce the fitness of >70% of the ... Keywords: Caenorhabditis, elegans, gene drive natural, meiotic drive, selfish DNA, selfish genetic element, toxin antidote |
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A maternal-effect selfish genetic element in Caenorhabditis elegansE. Ben-David, A. Burga and L. Kruglyak, Science, 356:1051. 2017.![]() We discovered a selfish element causing embryonic lethality in crosses between wild strains of the nematode Caenorhabditis elegans. Keywords: Caenorhabditis, elegans, gene drive natural, meiotic drive, selfish DNA, selfish genetic element, toxin antidote |
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Poisons, antidotes, and selfish genesN. Phadnis, Science, 356:1013. 2017.![]() On page1051 of this issue, BenDavid et al . (3) chase down a serendipitous observation of an anomaly in genetic crosses to unmask a toxin-antidote type of selfish system in worms. Keywords: Caenorhabditis, elegans, gene drive natural, meiotic drive, selfish DNA, selfish genetic element, toxin antidote |

Contact
David O’Brochta
Foundation for the
National Institutes of Health
geneconvenevi@fnih.org
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