
Keywords: female meiotic drive
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Female meiotic drive in plants: mechanisms and dynamicsF. Finseth, Current Opinion in Genetics and Development, 82:102101. 2023.![]() Female meiosis is fundamentally asymmetric, creating an arena for genetic elements to compete for inclusion in the egg to maximize their transmission. Centromeres, as mediators of chromosomal segregation, are prime candidates to evolve via ‘female meiotic drive’. According to ... Keywords: female meiotic drive, gene drive natural, gene drive review, hybrid, hybrid sterility, inbred, inbreeding depression, incompatibility, line populations, meiotic drive, non-Mendelian inheritance, prezygotic reproductive isolation, segregation distortion, selection component analysis, selfish genetic element |
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Meiotic drive of noncentromeric loci in mammalian meiosis II eggsD. M. Silva and T. Akera, Curr Opin Genet Dev, 81:102082. 2023.![]() The germline produces haploid gametes through a specialized cell division called meiosis. In general, homologous chromosomes from each parent segregate randomly to the daughter cells during meiosis, providing parental alleles with an equal chance of transmission. Meiotic drivers ... Keywords: female meiotic drive, gene drive natural, gene drive review, hybrid, hybrid sterility, inbred, inbreeding depression, incompatibility, line populations, meiotic drive, non-Mendelian inheritance, prezygotic reproductive isolation, segregation distortion, selection component analysis, selfish genetic element |
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The evolutionary significance of meiotic driveJ. B. Searle and F. P.-M. de Villena, Heredity, 2022.![]() In this essay, we will focus on‘true meiotic drive’ where the distorted transmission does arise within meiosis itself (Zanders and Unckless2019),specifically in females. Here, the non-transmission of one of the products of meiotic division is inherent in the gametogenic ... Keywords: female meiotic drive, gene drive natural, gene drive review, hybrid, hybrid sterility, inbred, inbreeding depression, incompatibility, line populations, meiotic drive, non-Mendelian inheritance, prezygotic reproductive isolation, segregation distortion, selection component analysis, selfish genetic element |
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Mixed knobs in corn cobsP. Lamelza and M. A. Lampson, Genes and Development, 34:1110-1112. 2020.![]() In this issue of Genes & Development, Swentowsky and colleagues (pp. 1239-1251) show that two types of knobs, those composed of 180-bp and TR1 sequences, recruit their own novel and divergent kinesin-14 family members to form neocentromeres. Keywords: female meiotic drive, gene drive natural, gene drive review, hybrid, hybrid sterility, inbred, inbreeding depression, incompatibility, line populations, meiotic drive, non-Mendelian inheritance, prezygotic reproductive isolation, segregation distortion, selection component analysis, selfish genetic element |
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Distinct kinesin motors drive two types of maize neocentromeresK. W. Swentowsky, J. I. Gent, E. G. Lowry, V. Schubert, X. Ran, K. F. Tseng, A. E. Harkess, W. H. Qiu and R. K. Dawe, Genes and Development, 34:1239-1251. 2020.![]() Here we describe a second kinesin-14 gene, TR-1 kinesin (Trkin), that is required to mobilize neocentromeres made up of the minor tandem repeat TR-1. Keywords: female meiotic drive, gene drive natural, gene drive review, hybrid, hybrid sterility, inbred, inbreeding depression, incompatibility, line populations, meiotic drive, non-Mendelian inheritance, prezygotic reproductive isolation, segregation distortion, selection component analysis, selfish genetic element |
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Standard deviations: The biological bases of transmission ratio distortionL. Fishman and M. McIntosh, Annual Review of Genetics, 53:347-372. 2019.![]() The rule of Mendelian inheritance is remarkably robust, but deviations from the equal transmission of alternative alleles at a locus [a.k.a. transmission ratio distortion (TRD)] are also commonly observed in genetic mapping populations. Such TRD reveals locus-specific selection ... Keywords: female meiotic drive, gene drive natural, gene drive review, hybrid, hybrid sterility, inbred, inbreeding depression, incompatibility, line populations, meiotic drive, non-Mendelian inheritance, prezygotic reproductive isolation, segregation distortion, selection component analysis, selfish genetic element |

Contact
David O’Brochta
Foundation for the
National Institutes of Health
geneconvenevi@fnih.org
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