Keywords: female-specific lethality

femaleless Controls Sex Determination and Dosage Compensation Pathways in Females of Anopheles Mosquitoes

E. Krzywinska, L. Ferretti, J. Li, J.-C. Li, C.-H. Chen and J. Krzywinski,  Current Biology,  31:1084-1091.e4. 2021.
Here we show that in the African malaria mosquito Anopheles gambiae, a gene, which likely arose in the Anopheles lineage and which we call femaleless (fle), controls sex determination in females by regulating splicing of dsx and fruitless (fru; another terminal gene within a ...
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Genetic engineering of sex chromosomes for batch cultivation of non-transgenic, sex-sorted males

S. R. Das, M. Maselko, A. Upadhyay and M. J. Smanski,  PloS Genetics,  16:11. 2020.
The field performance of Sterile Insect Technique (SIT) is improved by sex-sorting and releasing only sterile males. This can be accomplished by resource-intensive separation of males from females by morphology. Alternatively, sex-ratio biasing genetic constructs can be used to ...
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