Keywords: fitness costs
Quantifying Fitness Costs in Transgenic Aedes aegypti MosquitoesWilliams, A. E., Sanchez-Vargas, I., Martin, L. E., Martin-Martin, I., Bennett, S., Olson, K. E., Calvo, E., The Journal of Visualized Experiments, 199. 2024.The present protocol describes how to measure common life parameter data in Aedes aegypti mosquitoes, including fecundity, wing size, fertility, sex ratio, viability, development times, male contribution, and adult longevity. Keywords: CRISPR-Cas9, fitness costs, gene drive natural, gene drive synthetic, meiotic drive, population suppression, selfish genetic elements, sex-ratio distorter, transposable element, wolbachia |
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Resistance to natural and synthetic gene drive systemsT. A. R. Price, N. Windbichler, R. L. Unckless, A. Sutter, J.-N. Runge, P. A. Ross, A. Pomiankowski, N. L. Nuckolls, C. Montchamp-Moreau, N. Mideo, O. Y. Martin, A. Manser, M. Legros, A. M. Larracuente, L. Holman, J. Godwin, N. Gemmell, C. Courret, A. Buc, Journal of Evolutionary Biology, 2020.This review summarizes our current knowledge of drive resistance in both natural and synthetic gene drives. We explore how insights from naturally occurring and synthetic drive systems can be integrated to improve the design of gene drives, better predict the outcome of releases ... Keywords: CRISPR-Cas9, fitness costs, gene drive natural, gene drive synthetic, meiotic drive, population suppression, selfish genetic elements, sex-ratio distorter, transposable element, wolbachia |
Contact
David O’Brochta
Foundation for the
National Institutes of Health
geneconvenevi@fnih.org
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