Keywords: fungus

Wolbachia enhances the survival ofDrosophila infected with fungal pathogens

J. Perlmutter, I., A. Atadurdyyeva, M. Schedl, E. and R. Unckless, L. ,  bioRxiv,  2023.09.30.560320. 2023.
Wolbachia bacteria of arthropods are at the forefront of basic and translational research on multipartite host-symbiont-pathogen interactions. These microbes are vertically inherited from mother to offspring via the cytoplasm. They are the most widespread endosymbionts on the ...
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A recombinant Aspergillus oryzae fungus transmitted from larvae to adults of Anopheles stephensi mosquitoes inhibits malaria parasite oocyst development

L. Kianifard, A. M. Rafiqi, O. Akcakir, A. S. I. Aly, P. F. Billingsley and S. Uysal,  Scientific Reports,  13:12177. 2023.
The control of malaria parasite transmission from mosquitoes to humans is hampered by decreasing efficacies of insecticides, development of drug resistance against the last-resort antimalarials, and the absence of effective vaccines. Herein, the anti-plasmodial transmission ...
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S. pombe wtf drivers use dual transcriptional regulation and selective protein exclusion from spores to cause meiotic drive

N. L. Nuckolls, A. Nidamangala Srinivasa, A. C. Mok, R. M. Helston, M. A. Bravo Núñez, J. J. Lange, T. J. Gallagher, C. W. Seidel and S. E. Zanders,  PLOS Genetics,  18:e1009847. 2022.
Author summary Genomes are often considered a collection of ‘good’ genes that provide beneficial functions for the organism. From this perspective, disease is thought to arise due to disfunction of ‘good’ genes. For example, infertility can be caused by the failure of a ...
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Cross-kingdom RNAi to enhance the efficacy of insect pathogens

S. Asgari,  Trends in Parasitology,  2022.
Insect pathogens play significant roles in the biocontrol of medical and agricultural pests. Cui et al. demonstrated that genetically modified (GM) fungi expressing host mosquito miRNAs could enhance the efficacy of the fungus by suppressing the host immune response. This opens ...
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