Keywords: gene drive genetic conflict segregation distortion selfish genetic elements toxin-antidote toxin-antitoxin

Toxin-Antidote Elements Across the Tree of Life

A. Burga, E. Ben-David and L. Kruglyak,  Annual Review Genetics,  54:387-415. 2020.
Toxin-antitoxin or toxin-antidote (TA) elements are genetic dyads that cheat the laws of inheritance to guarantee their transmission to the next generation. This seemingly simple genetic arrangement-a toxin linked to its antidote-is capable of quickly spreading and persisting in ...