Keywords: gene expression

Transgenic expression of cif genes from Wolbachia strain wAlbB recapitulates cytoplasmic incompatibility in Aedes aegypti

McNamara, C.J., Ant, T.H., Harvey-Samuel, T. et al.,  Nature Communications,  15. 2024.
The endosymbiotic bacteria Wolbachia can invade insect populations by modifying host reproduction through cytoplasmic incompatibility (CI), an effect that results in embryonic lethality when Wolbachia-carrying males mate with Wolbachia-free females. Here we describe a transgenic ...
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Efficient sex separation by exploiting differential alternative splicing of a dominant marker in Aedes aegypti

Shih-Che Weng, Igor Antoshechkin, Eric Marois, Omar S. Akbari,  PLoS Genetics,  2023.
Only female mosquitoes consume blood giving them the opportunity to transmit deadly human pathogens. Therefore, it is critical to remove females before conducting releases for genetic biocontrol interventions. Here we describe a robust sex-sorting approach termed SEPARATOR ...
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Effects of a male meiotic driver on male and female transcriptomes in the house mouse

A. Lindholm, A. Sutter, S. Kunzel, D. Tautz and H. Rehrauer,  Proceedings of the Royal Society B-Biological Sciences,  286:1-8. 2019.
Not all genetic loci follow Mendel's rules, and the evolutionary consequences of this are not yet fully known. Genomic conflict involving multiple loci is a likely outcome, as restoration of Mendelian inheritance patterns will be selected for, and sexual conflict may also arise ...
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