Keywords: genetic conflict

A selfish genetic element and its suppressor causes gross damage to testes in a fly

S. Lyth, A. Manser, G. Hurst, T. Price and R. Verspoor,  bioRxiv,  2023.02.06.527273. 2023.
Selfish genetic elements (SGEs), specifically X-chromosome meiotic drive (XCMD), create huge conflicts within a hosts genome and can have profound effects on fertility. Suppressors are a common evolutionary response to XCMD to negate its costs. However, whether suppressors ...
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Diverse mating phenotypes impact the spread of wtf meiotic drivers in Schizosaccharomyces pombe

J. F. L. Hernandez, R. M. Helston, J. J. Lange, R. B. Billmyre, S. H. Schaffner, M. T. Eickbush, S. McCroskey and S. E. Zanders,  Elife,  10:30. 2021.
Meiotic drivers are genetic elements that break Mendel's law of segregation to be transmitted into more than half of the offspring produced by a heterozygote. The success of a driver relies on outcrossing (mating between individuals from distinct lineages) because drivers gain ...
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Autosomal suppression and fitness costs of an old driving X chromosome in Drosophila testacea

G. Keais, S. Lu and S. Perlman,  Journal of Evolutionary Biology,  2020.
Driving X chromosomes (XDs) are meiotic drivers that bias their own transmission through males by killing Y-bearing gametes. These chromosomes can in theory spread rapidly in populations and cause extinction, but many are found as balanced polymorphisms or as ?cryptic? XDs shut ...
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