
Keywords: genetic conflict
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A selfish genetic element and its suppressor causes gross damage to testes in a flyS. Lyth, A. Manser, G. Hurst, T. Price and R. Verspoor, bioRxiv, 2023.02.06.527273. 2023.![]() Selfish genetic elements (SGEs), specifically X-chromosome meiotic drive (XCMD), create huge conflicts within a hosts genome and can have profound effects on fertility. Suppressors are a common evolutionary response to XCMD to negate its costs. However, whether suppressors ... Keywords: driving X, drosophila, gamete-killing, Gene drive, gene drvie natural, genetic conflict, genomic conflict, meiotic drive, segregation distortion, selfish genetic elements, sex-ratio, X chromosome |
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Diverse mating phenotypes impact the spread of wtf meiotic drivers in Schizosaccharomyces pombeJ. F. L. Hernandez, R. M. Helston, J. J. Lange, R. B. Billmyre, S. H. Schaffner, M. T. Eickbush, S. McCroskey and S. E. Zanders, Elife, 10:30. 2021.![]() Meiotic drivers are genetic elements that break Mendel's law of segregation to be transmitted into more than half of the offspring produced by a heterozygote. The success of a driver relies on outcrossing (mating between individuals from distinct lineages) because drivers gain ... Keywords: driving X, drosophila, gamete-killing, Gene drive, gene drvie natural, genetic conflict, genomic conflict, meiotic drive, segregation distortion, selfish genetic elements, sex-ratio, X chromosome |
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Autosomal suppression and fitness costs of an old driving X chromosome in Drosophila testaceaG. Keais, S. Lu and S. Perlman, Journal of Evolutionary Biology, 2020.![]() Driving X chromosomes (XDs) are meiotic drivers that bias their own transmission through males by killing Y-bearing gametes. These chromosomes can in theory spread rapidly in populations and cause extinction, but many are found as balanced polymorphisms or as ?cryptic? XDs shut ... Keywords: driving X, drosophila, gamete-killing, Gene drive, gene drvie natural, genetic conflict, genomic conflict, meiotic drive, segregation distortion, selfish genetic elements, sex-ratio, X chromosome |

Contact
David O’Brochta
Foundation for the
National Institutes of Health
geneconvenevi@fnih.org
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