genetic load - GeneConvene Virtual Institute

Keywords: genetic load

Requirements for effective malaria control with homing endonuclease genes

Deredec, AG, H. C. J.; Burt, A., Proceedings of the National Academy of Sciences of the United States of America, 108:e874-e880. 2011.

Malaria continues to impose a substantial burden on human health. We have previously proposed that biological approaches to control the mosquito vector of disease could be developed using homing endonuclease genes (HEGs), a class of selfish or parasitic gene that exists naturally ...
Keywords: adaptation, Aedes aegypti, Anopheles gambiae, biological control, competition, drosophila, dynamics, gene drive mechanisms, gene drive models, gene drive natural, genetic load, homing endonucleases, insects, mosquito, population, transmission, vector, vector control