
Keywords: genome engineering
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Rational engineering of a synthetic insect-bacterial mutualismY. Su, H.-C. Lin, L. S. Teh, F. Chevance, I. James, C. Mayfield, K. G. Golic, J. A. Gagnon, O. Rog and C. Dale, Current Biology, 2022.![]() Summary Many insects maintain mutualistic associations with bacterial endosymbionts, but little is known about how they originate in nature. In this study, we describe the establishment and manipulation of a synthetic insect-bacterial symbiosis in a weevil host. Following egg ... Keywords: Evolution, fitness, gene drive ecology, gene drive geneticss, gene drive synthetic, genome engineering, meiotic drive, Population genetics, selfish gene |
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Biologists engineered insect-bacterial mutualism in ‘bucket list’ achievementAnnonymous, @THEU, 2022.![]() A new paper in Current Biology authored by Crystal Su and other collaborators in the School of Biological Sciences describes the development of a novel, synthetic insect-bacterial symbiosis that is sustained through many insect generations by transovarial bacterial transmission. ... Keywords: Evolution, fitness, gene drive ecology, gene drive geneticss, gene drive synthetic, genome engineering, meiotic drive, Population genetics, selfish gene |
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Gene-drive-mediated extinction is thwarted by population structure and evolution of sib matingJ. J. Bull, C. H. Remien and S. M. Krone, Evolution Medicine and Public Health, 2019:66-81. 2019.![]() Genetic engineering combined with CRISPR technology has developed to the point that gene drives can, in theory, be engineered to cause extinction in countless species. Success of extinction programs now rests on the possibility of resistance evolution, which is largely unknown. ... Keywords: Evolution, fitness, gene drive ecology, gene drive geneticss, gene drive synthetic, genome engineering, meiotic drive, Population genetics, selfish gene |

Contact
David O’Brochta
Foundation for the
National Institutes of Health
geneconvenevi@fnih.org
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