
Keywords: GM mosquito
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Mark-release-recapture experiment in Burkina Faso demonstrates reduced fitness and dispersal of genetically-modified sterile malaria mosquitoesF. A. Yao, A.-A. Millogo, P. S. Epopa, A. North, F. Noulin, K. Dao, M. Drabo, C. Guissou, S. Kekele, M. Namountougou, R. K. Ouedraogo, L. Pare, N. Barry, R. Sanou, H. Wandaogo, R. K. Dabire, A. McKemey, F. Tripet and A. Diabaté, Nature Communications, 13:796. 2022.![]() Every year, malaria kills approximately 405,000 people in Sub-Saharan Africa, most of them children under the age of five years. In many countries, progress in malaria control has been threatened by the rapid spread of resistance to antimalarial drugs and insecticides. Novel ... Keywords: Anopheles, Gene drive, genetically engineered mosquitoes, GM mosquito, malaria, population modification, review, transgenic |
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A flavivirus-inducible gene expression system that modulates broad-spectrum antiviral activity against dengue and Zika virusesS.-C. Weng, Y.-X. Zhou and S.-H. Shiao, Insect Biochemistry and Molecular Biology, 142:103723. 2022.![]() Incidence of dengue virus (DENV) and Zika virus (ZIKV), two mosquito-borne flaviviruses, is increasing in large parts of the world. Vaccination and medication for these diseases are unsatisfactory. Here, we developed a novel antiviral approach, using a virus-inducible gene ... Keywords: Anopheles, Gene drive, genetically engineered mosquitoes, GM mosquito, malaria, population modification, review, transgenic |
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An Introduction to Containment Recommendations for Gene Drive Mosquitoes and the Laboratory Rearing of Genetically Engineered Mosquitoes in AfricaS. Higgs, Vector-Borne and Zoonotic Diseases, 2022.![]() The prospect of using genetically engineered arthropods to reduce the incidence of vector-borne diseases either indirectly by suppressing vector populations or directly by replacing wild-type vector species with less competent ones has long been discussed; however, only in the ... Keywords: Anopheles, Gene drive, genetically engineered mosquitoes, GM mosquito, malaria, population modification, review, transgenic |
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Preparing an Insectary in Burkina Faso to Support Research in Genetic Technologies for Malaria ControlC. Guissou, M. M. Quinlan, R. Sanou, R. K. Ouédraogo, M. Namountougou and A. Diabaté, Vector-Borne and Zoonotic Diseases, 2022.![]() The Institut de Recherche en Sciences de la Santé (IRSS) of Burkina Faso, West Africa, was the first African institution to import transgenic mosquitoes for research purposes. A shift from the culture of mosquito research to regulated biotechnology research and considerable ... Keywords: Anopheles, Gene drive, genetically engineered mosquitoes, GM mosquito, malaria, population modification, review, transgenic |
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Malaria vector control tools in emergency settings: What do experts think? Results from a DELPHI surveyC. Boete, S. Burza, E. Lasry, S. Moriana and W. Robertson, Conflict and Health, 15:11. 2021.![]() Background The use and implementation of novel tools for malaria control such as long lasting impregnated bednets (LLINs) and Indoor Residual Spraying (IRS) over the last decade has contributed to a substantial reduction in malaria burden globally. However numerous challenges ... Keywords: Anopheles, Gene drive, genetically engineered mosquitoes, GM mosquito, malaria, population modification, review, transgenic |
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No, genetically engineered mosquitoes aren’t about to be released in BerkeleyK. D. Rauch, Berkeleyside, 2021.![]() Judith Pierce, public outreach coordinator for the Alameda County Mosquito Abatement District, would like to make one thing clear: A release of genetically engineered mosquitoes is not coming to Berkeley — or anywhere in Alameda County — in the near future. Not to her ... Keywords: Anopheles, Gene drive, genetically engineered mosquitoes, GM mosquito, malaria, population modification, review, transgenic |
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In Real Life: GMOsquitoesNewsy, Newsy, 2021.![]() The release of genetically modified mosquitoes in Florida gives hope of reducing the spread of disease while causing concerns among some citizens. Keywords: Anopheles, Gene drive, genetically engineered mosquitoes, GM mosquito, malaria, population modification, review, transgenic |
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Uncle Sam’s Dangerous GameX. Ping, XINHUANET, 2021.![]() Since the very beginning, residents in Florida Keys doubted if the “self-limiting” gene of Genetically Modified (GM) mosquitoes brought and released there by Oxitec, a biotech firm, and approved by U.S. Environmental Protection Agency and Florida Keys Mosquito Control ... Keywords: Anopheles, Gene drive, genetically engineered mosquitoes, GM mosquito, malaria, population modification, review, transgenic |
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Fighting the world’s most deadly animal: the mosquitoM. Rozenbaum, Understanding Animal Research, 2021.![]() n the first, sterile male mosquitos are mass produced and released into the wild. These sterile males mate with wild females who then lay sterile eggs which will not hatch. This approach has been shown to reduce wild populations by as much as 90% in trials with Aedes aegypt. The ... Keywords: Anopheles, Gene drive, genetically engineered mosquitoes, GM mosquito, malaria, population modification, review, transgenic |
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Mosquito transgenesis for malaria controlS. Dong, Y. Dong, M. L. Simões and G. Dimopoulos, Trends in Parasitology, 2021.![]() Malaria is one of the deadliest diseases. Because of the ineffectiveness of current malaria-control methods, several novel mosquito vector-based control strategies have been proposed to supplement existing control strategies. Mosquito transgenesis and gene drive have emerged as ... Keywords: Anopheles, Gene drive, genetically engineered mosquitoes, GM mosquito, malaria, population modification, review, transgenic |
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CRISPR/Cas-9 mediated knock-in by homology dependent repair in the West Nile Virus vector Culex quinquefasciatus SayD.-K. Purusothaman, L. Shackleford, M. A. E. Anderson, T. Harvey-Samuel and L. Alphey, Scientific Reports, 11:14964. 2021.![]() Culex quinquefasciatus Say is a mosquito distributed in both tropical and subtropical regions of the world. It is a night-active, opportunistic blood-feeder and vectors many animal and human diseases, including West Nile Virus and avian malaria. Current vector control methods ... Keywords: Anopheles, Gene drive, genetically engineered mosquitoes, GM mosquito, malaria, population modification, review, transgenic |
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GM mosquitoes to fight malariaI. Khisa, The INDEPENDENT, 2021.![]() Scientists at the Uganda Virus Research Institute (UVRI) plans to undertake a research on genetically engineered mosquitoes to tackle malaria. Dr. Jonathan Kayondo, the principal investigator Target Malaria Uganda and Senior Research Officer at UVRI had an email interview with ... Keywords: Anopheles, Gene drive, genetically engineered mosquitoes, GM mosquito, malaria, population modification, review, transgenic |
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Fighting disease: How are genetically engineered mosquitoes regulated?A. Julie, Global News, 2021.![]() Mosquitoes have long been associated with the spread of diseases like malaria, dengue fever and the Zika virus. But scientists around the world have been exploring the possibility that mosquitoes could also be key to slowing the spread of disease. By genetically altering the DNA ... Keywords: Anopheles, Gene drive, genetically engineered mosquitoes, GM mosquito, malaria, population modification, review, transgenic |
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‘Death gene’ in genetically modified male mosquitoesJ. Goddard, The Times, 2021.![]() Tens of thousands of bio-engineered mosquitoes have taken flight in the Florida Keys under a pilot project that aims to breed insects programmed with a “death switch”. Genetically modified males produced by Oxitec — a British-founded biotechnology company — have begun ... Keywords: Anopheles, Gene drive, genetically engineered mosquitoes, GM mosquito, malaria, population modification, review, transgenic |
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First Genetically Modified Mosquitoes Released in U.S. Are Hatching NowD. Coffey, Scientific American, 2021.![]() This week, mosquito eggs placed in the Florida Keys are expected to hatch tens of thousands of genetically modified mosquitoes, a result of the first U.S. release of such insects in the wild. A biotechnology firm called Oxitec delivered the eggs in late April as part of a ... Keywords: Anopheles, Gene drive, genetically engineered mosquitoes, GM mosquito, malaria, population modification, review, transgenic |
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In a World-First, Genetically Modified Mosquitoes Are Hatching in the USB. Bergan, INTERSTING ENGINEERING, 2021.![]() Mosquito eggs placed in the Florida Keys are about to hatch tens of thousands of genetically altered mosquitos, the first such release of "synthetic" insects in the world, according to an initial report from Scientific American. Pilot program for genetically modified mosquitoes ... Keywords: Anopheles, Gene drive, genetically engineered mosquitoes, GM mosquito, malaria, population modification, review, transgenic |
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What Are GMO Mosquitoes and What Is Their Purpose?A. Krosofsky, GREENMATTERS, 2021.![]() Scientists have made GMO corn, strawberries, even many types of farm animals. Now, it seems, they have managed to genetically modify mosquitoes as well. But what is the purpose of GMO mosquitoes, and why would scientists go out of their way to create something that is already a ... Keywords: Anopheles, Gene drive, genetically engineered mosquitoes, GM mosquito, malaria, population modification, review, transgenic |
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CSOs raise alarm over genetically-engineered mosquitoes in NigeriaA. Oboh, Vanguard, 2020.![]() No fewer than 75 civil society organisations, CSOs, across the world have raised the alarm over moves to release genetically-modified mosquitoes in Nigeria, noting that the country was about to be used as a guinea pig for the project, which will endanger humans, biodiversity and ... Keywords: Anopheles, Gene drive, genetically engineered mosquitoes, GM mosquito, malaria, population modification, review, transgenic |
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Groups warn against release of genetically-engineered mosquitoes in NigeriaC. Onyesi, Daily Post, 2020.![]() C. Onyesi (2020). Daily Post. Over 75 Civil Society Organizations from Nigeria, Africa and the world have condemned moves to open the way for the release of genetically modified mosquitoes in Nigeria. Keywords: Anopheles, Gene drive, genetically engineered mosquitoes, GM mosquito, malaria, population modification, review, transgenic |
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Beyone the buzzC. Watson, The Journal Gazette, 2020.![]() Lately I have found I need to force myself to follow science stories about something besides the pandemic. A story I consider hopeful involves genetically modified mosquitoes; we are developing a new tool that can reduce disease and save lives. The goal is to dramatically ... Keywords: Anopheles, Gene drive, genetically engineered mosquitoes, GM mosquito, malaria, population modification, review, transgenic |
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Malaria: Over 75 CSOs raise alarm over plans to release nautically engineered mosquitoesNews Agency of Nigeria, WorldStage, 2020.![]() Mre than 75 Environmental Civil Society Organisations from Nigeria, Africa and other countries have condemned moves to open way for release of genetically modified mosquitoes to control malaria infection. The News Agency of Nigeria (NAN), reports that at a virtual meeting of ... Keywords: Anopheles, Gene drive, genetically engineered mosquitoes, GM mosquito, malaria, population modification, review, transgenic |
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GMO Mosquitoes to be launched in FloridaAdministration, Editorials 360, 2020.![]() In June 2020, the Florida Division of Agriculture and Shopper Providers gave the go-ahead to a plan to launch thousands and thousands of genetically engineered mosquitoes within the Florida Keys this summer time to battle mosquito-borne diseases.1 The plan follows the EPA’s ... Keywords: Anopheles, Gene drive, genetically engineered mosquitoes, GM mosquito, malaria, population modification, review, transgenic |
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EPA Approves Genetically Modified Mosquito Trial For Florida KeysNancy Klingener, WLRN, 2020.![]() A plan to test genetically modified mosquitoes in the Florida Keys has received approval from the federal government. Keywords: Anopheles, Gene drive, genetically engineered mosquitoes, GM mosquito, malaria, population modification, review, transgenic |
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Mutant mosquitoes one step closer to release in Florida, Texas this summer. Why?K. Camero, The Charlotte Observer, 2020.![]() The U.S. Environmental Protection Agency (EPA) approved an experimental use permit for the British biotech company Oxitec to test the modified mosquitoes in the U.S. for the first time, according to a statement from the agency Keywords: Anopheles, Gene drive, genetically engineered mosquitoes, GM mosquito, malaria, population modification, review, transgenic |
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Genetically Engineered Male Mosquitos to be Released in Florida and Other Parts of US to Curb Zika and Dengue SpreadStaff Reporter, The Science Times, 2020.![]() The Environmental Protection Agency has recently approved a new and controversial field test aimed at reducing their population. Keywords: Anopheles, Gene drive, genetically engineered mosquitoes, GM mosquito, malaria, population modification, review, transgenic |
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Swarms of genetically modified mosquitoes could soon be descending on FloridaA. J. Dellinger, Mic, 2020.![]() Mosquitoes are a pain in the ass, so much so that the Environmental Protection Agency has approved a new and controversial field test aimed at curbing their population. Keywords: Anopheles, Gene drive, genetically engineered mosquitoes, GM mosquito, malaria, population modification, review, transgenic |
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EPA Grants First Permit to Test Genetically Modified MosquitoesAdam Allington, Bloomberg Law, 2020.![]() British biotech company Oxitec Ltd was granted an experimental use permit to release a genetically engineered type of the mosquito species Aedes aegypti, which is a known vector of Zika virus and viruses that cause yellow fever and dengue fever, the Environmental Protection ... Keywords: Anopheles, Gene drive, genetically engineered mosquitoes, GM mosquito, malaria, population modification, review, transgenic |
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EPA Approves Experimental Use Permit to Test Innovative Biopesticide Tool to Better Protect Public HealthEPA, EPA, 2020.![]() Today, after extensive evaluation of the best available science and public input, the U.S. Environmental Protection Agency (EPA) has granted an experimental use permit (EUP) to Oxitec Ltd. to field test the use of genetically engineered Aedes aegypti mosquitoes as a way to reduce ... Keywords: Anopheles, Gene drive, genetically engineered mosquitoes, GM mosquito, malaria, population modification, review, transgenic |
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Genetically Modified Mosquitoes Probably Headed to Florida Keys to Fight ZikaT. Elfrink, Miami New Times, 2016.![]() The bad news: Zika is coming to Florida. This past Friday, two new cases of the virus linked to serious birth defects were reported in the state, and scientists believe it could spread rapidly come summer as mosquito populations explode. And we're still a long way away from a ... Keywords: Anopheles, Gene drive, genetically engineered mosquitoes, GM mosquito, malaria, population modification, review, transgenic |
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Malaria Control with Genetically Manipulated Insect VectorsL. Alphey, C. B. Beard, P. Billingsley, M. Coetzee, A. Crisanti, C. Curtis, P. Eggleston, C. Godfray, J. Hemingway, M. Jacobs-Lorena, A. A. James, F. C. Kafatos, L. G. Mukwaya, M. Paton, J. R. Powell, W. Schneider, T. W. Scott, B. Sina, R. Sinden, S. Sink, Science, 298:119. 2002.![]() At a recent workshop, experts discussed the benefits, risks, and research priorities associated with using genetically manipulated insects in the control of vector-borne diseases. Keywords: Anopheles, Gene drive, genetically engineered mosquitoes, GM mosquito, malaria, population modification, review, transgenic |

Contact
David O’Brochta
Foundation for the
National Institutes of Health
geneconvenevi@fnih.org
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