Keywords: GM mosquitoes
Intron-derived small RNAs for silencing viral RNAs in mosquito cellsP. Y. L. Tng, L. Z. Carabajal Paladino, M. A. E. Anderson, Z. N. Adelman, R. Fragkoudis, R. Noad and L. Alphey, PLOS Neglected Tropical Diseases, 16:e0010548. 2022.
Aedes aegypti and Ae. albopictus are the main vectors of mosquito-borne viruses of medical and veterinary significance. Many of these viruses have RNA genomes. Exogenously provided, e.g. transgene encoded, small RNAs could be used to inhibit virus replication, breaking the ...
Keywords: arbovirus, dengue, genetic biocontrol, GM mosquitoes, mosquito, transgenic mosquitoes
Foundation for the
National Institutes of Health