Biomphalaria glabrata Granulin Increases Resistance to Schistosoma mansoni Infection in Several Biomphalaria Species and Induces the Production of Reactive Oxygen Species by HaemocytesJ. R. Hambrook, A. A. Gharamah, E. A. Pila, S. Hussein and P. C. Hanington, Genes, 11:12. 2019.
In this study, we demonstrate that in vivo addition of Biomphalaria glabrata pro-granulin (BgGRN) can reduce Schistosoma mansoni infection success in numerous Biomphalaria sp. when challenged with different S. mansoni strains. We also demonstrate that cleavage of BgGRN into ...
Keywords: Biomphalaria glabrata, Compatibility, gene drive synthetic, granulin, host-parasite, invertebrate immunology, population modification, Schistosoma mansoni