Keywords: haplodiploid

Modelling homing suppression gene drive in haplodiploid organisms

Y. Liu and J. Champer,  Proceedings of the Royal Society B: Biological Sciences,  289:20220320. 2022.
Gene drives have shown great promise for suppression of pest populations.These engineered alleles can function by a variety of mechanisms, but themost common is the CRISPR homing drive, which converts wild-type allelesto drive alleles in the germline of heterozygotes. Some ...
Keywords: , , , , , ,

Modelling homing suppression gene drive in haplodiploid organisms

Y. Liu and J. Champer,  bioRxiv,  2021.10.12.464047. 2022.
Gene drives have shown great promise for suppression of pest populations. These engineered alleles can function by a variety of mechanisms, but the most common is the CRISPR homing drive, which converts wild-type alleles to drive alleles in the germline of heterozygotes. Some ...
Keywords: , , , , , ,

Modeling homing suppression gene drive in haplodiploid organisms

Y. Liu and J. Champer,  bioRxiv,  2021.10.12.464047. 2021.
Gene drives have shown great promise for suppression of pest populations. These engineered alleles can function by a variety of mechanisms, but the most common is the CRISPR homing drive, which converts wild-type alleles to drive alleles in the germline of heterozygotes. Some ...
Keywords: , , , , , ,

A gene drive does not spread easily in populations of the honey bee parasite Varroa destructor

N. R. Faber, A. B. Meiborg, G. R. McFarlane, G. Gorjanc and B. A. Harpur,  bioRxiv,  2021.04.30.442149. 2021.
Varroa mites (Varroa destructor) are the most significant threat to beekeeping worldwide. They are directly or indirectly responsible for millions of colony losses each year. Beekeepers are somewhat able to control Varroa populations through the use of physical and chemical ...
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The potential for a CRISPR gene drive to eradicate or suppress globally invasive social wasps

P. J. Lester, M. Bulgarella, J. W. Baty, P. K. Dearden, J. Guhlin and J. M. Kean,  Scientific Reports,  10:12398. 2020.
P. J. Lester, M. Bulgarella, J. W. Baty, P. K. Dearden, J. Guhlin and J. M. Kean (2020). Scientific Reports. doi: 10.1038/s41598-020-69259-6 Gene drives have potential for widespread and cost-efficient pest control, but are highly controversial. We examined a potential gene ...
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Can CRISPR gene drive work in pest and beneficial haplodiploid species?

J. Li, O. Aidlin Harari, A.-L. Doss, L. L. Walling, P. W. Atkinson, S. Morin and B. E. Tabashnik,  Evolutionary Applications,  2020.
Gene drives based on CRISPR/Cas9 have the potential to reduce the enormous harm inflicted by crop pests and insect vectors of human disease, as well as to bolster valued species. In contrast with extensive empirical and theoretical studies in diploid organisms, little is known ...
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Simulation models from: Can CRISPER-mediated gene drive work in pest and beneficial haplodiploid species?

J. Li and B. Tabashnik,  Dryad,  2020.
Gene drives based on CRISPR/Cas9 have the potential to reduce the enormous harm inflicted by crop pests and insect vectors of human disease, as well as to bolster valued species. In contrast with extensive empirical and theoretical studies in diploid organisms, little is known ...
Keywords: , , , , , ,