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D. S. Bisht, V. Bhatia and R. Bhattacharya,
Seminars in Cell & Developmental Biology,
96:65-76.
2019.
The advantages of high input agriculture are fading away due to degenerating soil health and adverse effects of climate change. Safeguarding crop yields in the changing environment and dynamics of pest and pathogens, has posed new challenges to global agriculture. Thus, ...
Keywords: cre recombinase, DNA, drosophila-melanogaster, endonuclease genes, Evolution, gene drive evolution, gene drive models, gene drive natural, gene drive synthetic, history 2000-present, Homing, homing endonuclease, homologous recombination, horizontal transfer, intron, mechanisms, population eradication, population genetic engineering, protein, vector-borne diseases
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Posey, KLK, V.; Burt, A.; Gimble, F. S.,
Nucleic Acids Research,
32:3947-3956.
2004.
Homing endonuclease genes (HEGs) are mobile DNA elements that are thought to confer no benefit to their host. They encode site-specific DNA endonucleases that perpetuate the element within a species population by homing and disseminate it between species by horizontal transfer. ...
Keywords: cre recombinase, DNA, drosophila-melanogaster, endonuclease genes, Evolution, gene drive evolution, gene drive models, gene drive natural, gene drive synthetic, history 2000-present, Homing, homing endonuclease, homologous recombination, horizontal transfer, intron, mechanisms, population eradication, population genetic engineering, protein, vector-borne diseases
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Burt, A,
Proceedings of the Royal Society B-Biological Sciences,
270:921-928.
2003.
Site-specific selfish genes exploit host functions to copy themselves into a defined target DNA sequence, and include homing endonuclease genes, group II introns and some LINE-like transposable elements. If such genes can be engineered to target new host sequences, then they can ...
Keywords: cre recombinase, DNA, drosophila-melanogaster, endonuclease genes, Evolution, gene drive evolution, gene drive models, gene drive natural, gene drive synthetic, history 2000-present, Homing, homing endonuclease, homologous recombination, horizontal transfer, intron, mechanisms, population eradication, population genetic engineering, protein, vector-borne diseases
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