Keywords: house mice

Effects of a male meiotic driver on male and female transcriptomes in the house mouse

A. Lindholm, A. Sutter, S. Kunzel, D. Tautz and H. Rehrauer,  Proceedings of the Royal Society B-Biological Sciences,  286:1-8. 2019.
Not all genetic loci follow Mendel's rules, and the evolutionary consequences of this are not yet fully known. Genomic conflict involving multiple loci is a likely outcome, as restoration of Mendelian inheritance patterns will be selected for, and sexual conflict may also arise ...
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Pest demography critically determines the viability of synthetic gene drives for population control

K. E. Wilkins, T. A. A. Prowse, P. Cassey, P. Q. Thomas and J. V. Ross,  Mathematical Biosciences,  305:160-169. 2018.
Synthetic gene drives offer a novel solution for the control of invasive alien species. CRISPR-based gene drives can positively bias their own inheritance, and comprise a DNA sequence that is replicated by homologous recombination. Since gene drives can be positioned to silence ...
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