
Keywords: impacts
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Sustainability as a framework for considering gene drive mice for invasive rodent eradicationBarnhill-Dilling, SKS, M.; Blondel, D. V.; Godwin, J., Sustainability, 11:1334. 2019.![]() Gene drives represent a dynamic and controversial set of technologies with applications that range from mosquito control to the conservation of biological diversity on islands. Currently, gene drives are being developed in mice that may one day serve as an important tool for ... Keywords: cats, Evolution, fitness, genetic biocontrol, genome, impacts, intergenomic conflict, islands, male infertility, male-harming mutations, mice, mito-nuclear, mother's curse, mtDNA, pest control, population, selection, sterile male, technique, trojan female |
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Is it time for synthetic biodiversity conservation?Piaggio, AJS, G.; Seddon, P. J.; Alphey, L.; Bennett, E. L.; Carlson, R. H.; Friedman, R. M.; Kanavy, D.; Phelan, R.; Redford, K. H.; Rosales, M.; Slobodian, L.; Wheeler, K., Trends in Ecology & Evolution, 32:97-107. 2017.![]() Evidence indicates that, despite some critical successes, current conservation approaches are not slowing the overall rate of biodiversity loss. The field of synthetic biology, which is capable of altering natural genomes with extremely precise editing, might offer the potential ... Keywords: cats, Evolution, fitness, genetic biocontrol, genome, impacts, intergenomic conflict, islands, male infertility, male-harming mutations, mice, mito-nuclear, mother's curse, mtDNA, pest control, population, selection, sterile male, technique, trojan female |
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The Trojan Female Technique for pest control: a candidate mitochondrial mutation confers low male fertility across diverse nuclear backgrounds in Drosophila melanogasterD. K. Dowling, D. M. Tompkins and N. J. Gemmell, Evolutionary Applications, 8:8710880. 2015.![]() The Trojan Female Technique (TFT) was recently proposed as a prospective approach to biological pest control. However, applicability of the TFT relies on mitochondrial mutations whose male-sterilizing effects are general across nuclear genomic contexts. We test this assumption, ... Keywords: cats, Evolution, fitness, genetic biocontrol, genome, impacts, intergenomic conflict, islands, male infertility, male-harming mutations, mice, mito-nuclear, mother's curse, mtDNA, pest control, population, selection, sterile male, technique, trojan female |

Contact
David O’Brochta
Foundation for the
National Institutes of Health
geneconvenevi@fnih.org
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