Keywords: inbreeding
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Gene drives and population persistence vs elimination: The impact of spatial structure and inbreeding at low densityP. J. Beaghton and A. Burt, Theoretical Population Biology, 2022.
Synthetic gene drive constructs are being developed to control disease vectors, invasive species, and other pest species. In a well-mixed random mating population a sufficiently strong gene drive is expected to eliminate a target population, but it is not clear whether the same ... |
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Gene drives and population persistence vs elimination: the impact of spatial structure and inbreeding at low densityP. J. Beaghton and A. Burt, bioRxiv, 2021.11.11.468225. 2021.
Synthetic gene drive constructs are being developed to control disease vectors, invasive species, and other pest species. In a well-mixed random mating population a sufficiently strong gene drive is expected to eliminate a target population, but it is not clear whether the same ... |
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Gene drive escape from resistance depends on mechanism and ecologyF. Cook, J. J. Bull and R. Gomulkiewicz, bioRxiv, 2021.08.30.458221. 2021.
Gene drives can potentially be used to suppress pest populations, and the advent of CRISPR technology has made it feasible to engineer them in many species, especially insects. What remains largely unknown for implementations is whether anti-drive resistance will evolve to block ... |
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Lethal Gene Drive Selects InbreedingJ. J. Bull, bioRxiv, 046847. 2016.
ere, population genetic models are used to consider the evolution of inbreeding (specifically selfing) as a possible response to a recessively lethal HEG with complete segregation distortion. Numerical analyses indicate a rich set of outcomes, but selfing often evolves in ... |
