
Keywords: Indonesia
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Impact of randomised wmel Wolbachia deployments on notified dengue cases and insecticide fogging for dengue control in Yogyakarta CityC. Indriani, S. K. Tanamas, U. Khasanah, M. R. Ansari, Rubangi, W. Tantowijoyo, R. A. Ahmad, S. M. Dufault, N. P. Jewell, A. Utarini, C. P. Simmons and K. L. Anders, Glob Health Action, 16:2166650. 2023.![]() BACKGROUND: Releases of Wolbachia (wMel)-infected Aedes aegypti mosquitoes significantly reduced the incidence of virologically confirmed dengue in a previous cluster randomised trial in Yogyakarta City, Indonesia. Following the trial, wMel releases were extended to the untreated ... Keywords: Aedes aegypti, cytoplasmic incompatibility, dengue, genetic biocontrol, Indonesia, population replacement, wolbachia |
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Manipulated Mosquitoes Cut Dengue by 77%T. Hayes, Healthcare Packaging, 2021.Dengue, a mosquito-borne viral disease, wasn’t that common 50 years ago. In fact, only nine countries had severe outbreaks. But since then, it’s been on a steady incline to the point that there are now 400 million infections a year that contribute to 22,000 deaths. ... Keywords: Aedes aegypti, cytoplasmic incompatibility, dengue, genetic biocontrol, Indonesia, population replacement, wolbachia |
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Dengue fever: Upstaged but not outmatched by COVID-19C. E. Baclig, INQUIRER.NET, 2021.![]() Science has made gains in the war on dengue and other diseases that mosquitoes carry, like malaria.One of these is the World Mosquito Program (WMP), a non-profit initiative that aims to protect the global community from mosquito-borne viral diseases, by deploying a natural ... Keywords: Aedes aegypti, cytoplasmic incompatibility, dengue, genetic biocontrol, Indonesia, population replacement, wolbachia |
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Dengue Infections Can Be Sharply Reduced With Wolbachia BacteriaJ. Stone, Medscape, 2021.![]() A modestly titled new study released in the New England Journal of Medicine belies the extraordinary 77% protective efficacy reported for preventing dengue infections with Wolbachia-infected Aedes aegypti mosquitoes. A cluster-randomized clinical trial, the AWED ("Applying ... Keywords: Aedes aegypti, cytoplasmic incompatibility, dengue, genetic biocontrol, Indonesia, population replacement, wolbachia |
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Making mosquitoes to fight mosquitoes to prevent dengueA. George, Times of India, 2021.![]() In 2017, Delhi Chief Minister Arvind Kejriwal tweeted that the national capitl needed to be made mosquito-free. The same year, his Kerala counterpart, Pinaray Vijayan, called a three-day state-wide cleanliness drive as hospitals filled with genue patients. Keywords: Aedes aegypti, cytoplasmic incompatibility, dengue, genetic biocontrol, Indonesia, population replacement, wolbachia |
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Dengue Fever Cut Down by 77% With Groundbreaking Bacteria-Armed MosquitoesM. Davis, The Science Times, 2021.![]() Scientists found that dengue fever cases have decreased by 77% in a groundbreaking trial that took place in Yogyakarta City, Indonesia. They used Wolbachia-infected mosquitoes that reduced their ability to spread the dengue fever. The team at the World Mosquito Program said that ... Keywords: Aedes aegypti, cytoplasmic incompatibility, dengue, genetic biocontrol, Indonesia, population replacement, wolbachia |
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Mosquito ‘bacteria hack’ nearly eliminates dengue fever and could save millions of livesA. Wilkins, METRO, 2021.![]() Mosquitoes infected with a ‘miraculous’ bacteria have been shown to reduce dengue fever cases by 77%, in a groundbreaking new study. Scientists released mosquitoes infected with ‘Wolbachia’ bacteria into the Indonesian city of Yogyakarta – but only in certain zones. In ... Keywords: Aedes aegypti, cytoplasmic incompatibility, dengue, genetic biocontrol, Indonesia, population replacement, wolbachia |
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‘Miraculous’ mosquito hack cuts dengue by 77%J. Gallagher, BBC, 2021.![]() Dengue fever cases have been cut by 77% in a "groundbreaking" trial that manipulates the mosquitoes that spread it, say scientists. They used mosquitoes infected with "miraculous" bacteria that reduce the insect's ability to spread dengue. The trial took place in Yogyakarta city, ... Keywords: Aedes aegypti, cytoplasmic incompatibility, dengue, genetic biocontrol, Indonesia, population replacement, wolbachia |
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Modified mosquitoes reduce dengue cases by 77% in Indonesia experimentM. Fox, CNN, 2021.![]() An experiment to infect mosquitoes with bacteria that stop them from transmitting viruses appears to have helped reduced the spread of deadly dengue virus in Indonesia, researchers reported Wednesday. The modified mosquitoes thrived for three years, and cases of dengue were ... Keywords: Aedes aegypti, cytoplasmic incompatibility, dengue, genetic biocontrol, Indonesia, population replacement, wolbachia |
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Efficacy of Wolbachia-Infected Mosquito Deployments for the Control of DengueA. Utarini, C. Indriani, R. A. Ahmad, W. Tantowijoyo, E. Arguni, M. R. Ansari, E. Supriyati, D. S. Wardana, Y. Meitika, I. Ernesia, I. Nurhayati, E. Prabowo, B. Andari, B. R. Green, L. Hodgson, Z. Cutcher, E. Rancès, P. A. Ryan, S. L. O’Neill, S. M. Dufau, New England Journal of Medicine, 384:2177-2186. 2021.![]() BACKGROUND Aedes aegypti mosquitoes infected with the wMel strain of Wolbachia pipientis are less susceptible than wild-type A. aegypti to dengue virus infection. METHODS We conducted a cluster-randomized trial involving releases of wMel-infected A. aegypti mosquitoes for the ... Keywords: Aedes aegypti, cytoplasmic incompatibility, dengue, genetic biocontrol, Indonesia, population replacement, wolbachia |
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Mosquitoes armed with virus-fighting bacteria sharply curb dengue infections, hospitalizationsK. Servick, Science, 2021.![]() A strategy for fighting dengue fever with bacteria-armed mosquitoes has passed its most rigorous test yet: a large, randomized, controlled trial. Researchers reported today dramatic reductions in rates of dengue infection and hospitalization in areas of an Indonesian city where ... Keywords: Aedes aegypti, cytoplasmic incompatibility, dengue, genetic biocontrol, Indonesia, population replacement, wolbachia |
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Study demonstrates ‘exciting potential’ of Wolbachia-infected mosquitoes to control dengueG. Gallagher, Healio, 2021.![]() The release of Wolbachia-infected mosquitoes led to a 77% reduction in the incidence of symptomatic dengue in an Indonesian city, according to researchers, who said the same approach could be used to fight other mosquito-borne diseases. The study tested a strain of Wolbachia ... Keywords: Aedes aegypti, cytoplasmic incompatibility, dengue, genetic biocontrol, Indonesia, population replacement, wolbachia |
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The potential cost-effectiveness of controlling dengue in Indonesia using wMel Wolbachia released at scale: a modelling studyO. J. Brady, D. D. Kharisma, N. N. Wilastonegoro, K. M. Reilly, E. Hendricx, L. S. Bastos, L. Yakob and D. S. Shepard, medRxiv, 2020.01.11.20017186. 2020.![]() Wolbachia releases in high density urban areas is expected to be highly cost-effective and could potentially be the first cost saving intervention for dengue. Sites with strong public health infrastructure, fiscal capacity, and community support should be prioritized. Keywords: Aedes aegypti, cytoplasmic incompatibility, dengue, genetic biocontrol, Indonesia, population replacement, wolbachia |

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