Keywords: insect immunity

Expression of mosquito miRNAs in entomopathogenic fungus induces pathogen-mediated host RNA interference and increases fungal efficacy

C. Cui, Y. Wang, Y. Li, P. Sun, J. Jiang, H. Zhou, J. Liu and S. Wang,  Cell Reports,  41:111527. 2022.
Summary The growing threat of insecticide resistance prompts the urgent need to develop additional tools for mosquito control. Entomopathogenic fungi provide an eco-friendly alternative to chemical insecticides. One limitation to the use of mycoinsecticides is their relatively ...
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Cross-kingdom RNAi to enhance the efficacy of insect pathogens

S. Asgari,  Trends in Parasitology,  2022.
Insect pathogens play significant roles in the biocontrol of medical and agricultural pests. Cui et al. demonstrated that genetically modified (GM) fungi expressing host mosquito miRNAs could enhance the efficacy of the fungus by suppressing the host immune response. This opens ...
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