Site-specific selfish genes as tools for the control and genetic engineering of natural populationsBurt, A, Proceedings of the Royal Society B-Biological Sciences, 270:921-928. 2003.
Site-specific selfish genes exploit host functions to copy themselves into a defined target DNA sequence, and include homing endonuclease genes, group II introns and some LINE-like transposable elements. If such genes can be engineered to target new host sequences, then they can ...
Keywords: cre recombinase, DNA, drosophila-melanogaster, endonuclease genes, Evolution, gene drive evolution, gene drive models, gene drive natural, gene drive synthetic, history 2000-present, Homing, homing endonuclease, homologous recombination, horizontal transfer, intron, mechanisms, population eradication, population genetic engineering, protein, vector-borne diseases
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