
Keywords: invasive rodents
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Gene drive technology to suppress invasive miceUniversity of Adelaide, Phys Org, 2022.![]() Researchers at the University of Adelaide have released their first findings on the potential effectiveness of revolutionary gene drive technology to control invasive mice. The team has developed a world-first proof of concept for the technology—called t-CRISPR—using ... Keywords: competition, conservation, CRISPR, Gene drive, gene drive natural, gene drive synthetic, genetic biocontrol, invasive rodents, invasive species, mice, mus-musculus, Pest management, reproductive fitness t haplotype |
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Leveraging a natural murine meiotic drive to suppress invasive populationsL. Gierus, A. Birand, M. D. Bunting, G. I. Godahewa, S. G. Piltz, K. P. Oh, A. J. Piaggio, D. W. Threadgill, J. Godwin, O. Edwards, P. Cassey, J. V. Ross, T. A. A. Prowse and P. Q. Thomas, Proceedings of the National Academy of Sciences, 119:e2213308119. 2022.![]() Invasive rodents are a major cause of environmental damage and biodiversity loss, particularly on islands. Unlike insects, genetic biocontrol strategies including population-suppressing gene drives with biased inheritance have not been developed in mice. Here, we demonstrate a ... Keywords: competition, conservation, CRISPR, Gene drive, gene drive natural, gene drive synthetic, genetic biocontrol, invasive rodents, invasive species, mice, mus-musculus, Pest management, reproductive fitness t haplotype |
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Towards a genetic approach to invasive rodent eradications: assessing reproductive competitiveness between wild and laboratory miceM. Serr, N. Heard and J. Godwin, Island invasives: scaling up to meet the challenge, 2019.![]() House mice are significant invasive pests, particularly on islands without native mammalian predators. As part of a multi-institutional project aimed at suppressing invasive mouse populations on islands, we aim to create heavily male-biased sex ratios with the goal of causing the ... Keywords: competition, conservation, CRISPR, Gene drive, gene drive natural, gene drive synthetic, genetic biocontrol, invasive rodents, invasive species, mice, mus-musculus, Pest management, reproductive fitness t haplotype |

Contact
David O’Brochta
Foundation for the
National Institutes of Health
geneconvenevi@fnih.org
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