Keywords: Life Sciences & Biomedicine - Other Topics

	A Y-chromosome shredding gene drive for controlling pest vertebrate populations Prowse, TAAA, F.; Cassey, P.; Thomas, P.; Ross, J. V.,  eLife,  8:19. 2019. Self-replicating gene drives that modify sex ratios or infer a fitness cost could be used to control populations of invasive alien species. The targeted deletion of Y sex chromosomes using CRISPR technology offers a new approach for sex bias that could be incorporated within ... Keywords: Gene drive, gene drive guidance, gene drive safety, gene drive synthetic, genome, global conservation, horizon, infectious-diseases, Life Sciences & Biomedicine - Other Topics, microbiome, organisms, photosynthesis, scan, science, Synthetic biology
	Controlling invasive rodents via synthetic gene drive and the role of polyandry Manser, AC, S. J.; Sutter, A.; Blondel, D. V.; Serr, M.; Godwin, J.; Price, T. A. R.,  Proceedings of the Royal Society B-Biological Sciences,  286:9. 2019. House mice are a major ecosystem pest, particularly threatening island ecosystems as a non-native invasive species. Rapid advances in synthetic biology offer new avenues to control pest species for biodiversity conservation. Recently, a synthetic sperm-killing gene drive ... Keywords: Gene drive, gene drive guidance, gene drive safety, gene drive synthetic, genome, global conservation, horizon, infectious-diseases, Life Sciences & Biomedicine - Other Topics, microbiome, organisms, photosynthesis, scan, science, Synthetic biology
	Genetic conflicts: the usual suspects and beyond McLaughlin, RNM, H. S.,  Journal of Experimental Biology,  220:6-17. 2017. Selfishness is pervasive and manifests at all scales of biology, from societies, to individuals, to genetic elements within a genome. The relentless struggle to seek evolutionary advantages drives perpetual cycles of adaptation and counter-adaptation, commonly referred to as Red ... Keywords: Gene drive, gene drive guidance, gene drive safety, gene drive synthetic, genome, global conservation, horizon, infectious-diseases, Life Sciences & Biomedicine - Other Topics, microbiome, organisms, photosynthesis, scan, science, Synthetic biology
	A transatlantic perspective on 20 emerging issues in biological engineering Wintle, BCB, C. R.; Rhodes, C.; Molloy, J. C.; Millett, P.; Adam, L.; Breitling, R.; Carlson, R.; Casagrande, R.; Dando, M.; Doubleday, R.; Drexler, E.; Edwards, B.; Ellis, T.; Evans, N. G.; Hammond, R.; Haseloff, J.; Kahl, L.; Kuiken, T.; Lichman, B. R.; Matthewman, C. A.; Napier, J. A.; OhEigeartaigh, S. S.; Patron, N. J.; Perello, E.; Shapira, P.; Tait, J.; Takano, E.; Sutherland, W. J.,  eLife,  6:21. 2017. Advances in biological engineering are likely to have substantial impacts on global society. To explore these potential impacts we ran a horizon scanning exercise to capture a range of perspectives on the opportunities and risks presented by biological engineering. We first ... Keywords: Gene drive, gene drive guidance, gene drive safety, gene drive synthetic, genome, global conservation, horizon, infectious-diseases, Life Sciences & Biomedicine - Other Topics, microbiome, organisms, photosynthesis, scan, science, Synthetic biology