Keywords: Loss of function

Modeling the mutation and reversal of engineered underdominance gene drives

Edgington, MPA, Luke S.,  Journal of Theoretical Biology,  479:14-21. 2019.
A range of gene drive systems have been proposed that are predicted to increase their frequency and that of associated desirable genetic material even if they confer a fitness cost on individuals carrying them. Engineered underdominance (UD) is such a system and, in one version, ...
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