Keywords: meitoic drive

Chromosome drives via CRISPR-Cas9 in yeast

H. Xu, M. Han, S. Zhou, B.-Z. Li, Y. Wu and Y.-J. Yuan,  Nature Communications,  11:4344. 2020.
Our results show that the entire Saccharomyces cerevisiae chromosome can be eliminated efficiently through only one double-strand break around the centromere via CRISPR-Cas9. As a proof-of-concept experiment of this CRISPR-Cas9 chromosome drive system, the synthetic yeast ...
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Veni, vidi, vici: the success of wtf meiotic drivers in fission yeast

López Hernández, JFZ, Sarah E.,  Yeast,  35:447-453. 2018.
Meiotic drivers are selfish DNA loci that can bias their own transmission into gametes. Owing to their transmission advantages, meiotic drivers can spread in populations even if the drivers or linked variants decrease organismal fitness. Meiotic drive was first formally described ...
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Sex ratio distorter reduces sperm competitive ability in an insect

Price, TARB, A. J.; Avent, T. D.; Snook, R. R.; Hurst, G. D. D.; Wedell, N.,  Evolution,  62:1644-1652. 2008.
Selfish genetic elements (SGEs) are ubiquitous in animals and often associated with low male fertility due to reduced sperm number in male carriers. In the fruit fly Drosophila pseudoobscura, the meiotic driving X chromosome "sex ratio" kills Y-bearing sperm in carrier males (SR ...
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Measuring meiotic drive

Robbins, LGP, G.; Bonaccorsi, S.; Pimpinelli, S.,  Genetics,  142:645-647. 1996.
LAURENCE HURST’S (1996) letter re-examines our data on the effect of Stellate copy number on the meiotic parameters of Mystal- (= su(ste)-) males (PALUMBO et al. 1994). In our analysis, we found a tight correlation of fertility and disjunction with Stellate copy number, with ...
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