Keywords: Mendelian DNA

Allele Sails: launching traits and fates into wild populations with Mendelian DNA sequence modifiers

Michelle L. Johnson, Bruce A. Hay, Maciej Maselko,  bioRxiv,  2024.
Population-scale genome editing can be used to alter the composition or fate of wild populations. One approach to achieving these aims utilizes a synthetic gene drive element—a multi-gene cassette—to bring about an increase in the frequency of an existing allele. However, the ...
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