Keywords: microbiome
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Combining transgenesis with paratransgenesis to fight malariaW. Huang, J. Vega-Rodriguez, C. Kizito, S.-J. Cha and M. Jacobs-Lorena, eLife, 11:e77584. 2022.
Malaria is among the deadliest infectious diseases, and Plasmodium, the causative agent, needs to complete a complex development cycle in its vector mosquito for transmission to occur. Two promising strategies to curb transmission are transgenesis, consisting of genetically ... |
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Aedes aegypti and Ae. albopictus microbiome/virome: new strategies for controlling arboviral transmission?M. Gómez, D. Martinez, M. Muñoz and J. D. Ramírez, Parasites and Vectors, 15:287. 2022.
Aedes aegypti and Aedes albopictus are the main vectors of highly pathogenic viruses for humans, such as dengue (DENV), chikungunya (CHIKV), and Zika (ZIKV), which cause febrile, hemorrhagic, and neurological diseases and remain a major threat to global public health. The high ... |
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Wolbachia interacts with the microbiome to shape fitness-associated traits during seasonal adaptation in Drosophila melanogasterL. P. Henry, M. Fernandez, S. Wolf and J. Ayroles, bioRxiv, 2022.05.31.494239. 2022.
The microbiome contributes to many different host traits, but its role in host adaptation remains enigmatic. The fitness benefits of the microbiome often depend on ecological conditions, but fluctuations in both the microbiome and environment modulate these fitness benefits. ... |
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A natural symbiotic bacterium drives mosquito refractoriness to Plasmodium infection via secretion of an antimalarial lipaseH. Gao, L. Bai, Y. M. Jiang, W. Huang, L. L. Wang, S. G. Li, G. D. Zhu, D. Q. Wang, Z. H. Huang, X. S. Li, J. Cao, L. B. Jiang, M. Jacobs-Lorena, S. Zhan and S. B. Wang, Nature Microbiology, 25. 2021.
The stalling global progress in the fight against malaria prompts the urgent need to develop new intervention strategies. Whilst engineered symbiotic bacteria have been shown to confer mosquito resistance to parasite infection, a major challenge for field implementation is to ... |
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Engineering a Culturable Serratia symbiotica Strain for Aphid ParatransgenesisK. M. Elston, J. Perreau, G. P. Maeda, N. A. Moran and J. E. Barrick, Applied Environmental Microbiology, 87. 2020.
Aphids are global agricultural pests and important models for bacterial symbiosis. To date, none of the native symbionts of aphids have been genetically manipulated, which limits our understanding of how they interact with their hosts. Serratia symbiotica CWBI-2.3(T) is a ... |
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Microbiome Innovation in Agriculture: Development of Microbial Based Tools for Insect Pest ManagementM. Qadri, S. Short, K. Gast, J. Hernandez and A. C.-N. Wong, Frontiers in Sustainable Food Systems, 4. 2020.
This review emphasizes the potential and use of microbes in sustainable insect pest management. We first review the diverse insect traits shaped by insect-microbe associations that span nutrition, immunity, ecological interactions with natural enemy, insecticide resistance, and ... |
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A transatlantic perspective on 20 emerging issues in biological engineeringWintle, BCB, C. R.; Rhodes, C.; Molloy, J. C.; Millett, P.; Adam, L.; Breitling, R.; Carlson, R.; Casagrande, R.; Dando, M.; Doubleday, R.; Drexler, E.; Edwards, B.; Ellis, T.; Evans, N. G.; Hammond, R.; Haseloff, J.; Kahl, L.; Kuiken, T.; Lichman, B. R.; Matthewman, C. A.; Napier, J. A.; OhEigeartaigh, S. S.; Patron, N. J.; Perello, E.; Shapira, P.; Tait, J.; Takano, E.; Sutherland, W. J., eLife, 6:21. 2017.
Advances in biological engineering are likely to have substantial impacts on global society. To explore these potential impacts we ran a horizon scanning exercise to capture a range of perspectives on the opportunities and risks presented by biological engineering. We first ... |
Keywords: microbiome
|
|
Combining transgenesis with paratransgenesis to fight malariaW. Huang, J. Vega-Rodriguez, C. Kizito, S.-J. Cha and M. Jacobs-Lorena, eLife, 11:e77584. 2022.
Malaria is among the deadliest infectious diseases, and Plasmodium, the causative agent, needs to complete a complex development cycle in its vector mosquito for transmission to occur. Two promising strategies to curb transmission are transgenesis, consisting of genetically ... |
|
|
Aedes aegypti and Ae. albopictus microbiome/virome: new strategies for controlling arboviral transmission?M. Gómez, D. Martinez, M. Muñoz and J. D. Ramírez, Parasites and Vectors, 15:287. 2022.
Aedes aegypti and Aedes albopictus are the main vectors of highly pathogenic viruses for humans, such as dengue (DENV), chikungunya (CHIKV), and Zika (ZIKV), which cause febrile, hemorrhagic, and neurological diseases and remain a major threat to global public health. The high ... |
|
|
Wolbachia interacts with the microbiome to shape fitness-associated traits during seasonal adaptation in Drosophila melanogasterL. P. Henry, M. Fernandez, S. Wolf and J. Ayroles, bioRxiv, 2022.05.31.494239. 2022.
The microbiome contributes to many different host traits, but its role in host adaptation remains enigmatic. The fitness benefits of the microbiome often depend on ecological conditions, but fluctuations in both the microbiome and environment modulate these fitness benefits. ... |
|
|
A natural symbiotic bacterium drives mosquito refractoriness to Plasmodium infection via secretion of an antimalarial lipaseH. Gao, L. Bai, Y. M. Jiang, W. Huang, L. L. Wang, S. G. Li, G. D. Zhu, D. Q. Wang, Z. H. Huang, X. S. Li, J. Cao, L. B. Jiang, M. Jacobs-Lorena, S. Zhan and S. B. Wang, Nature Microbiology, 25. 2021.
The stalling global progress in the fight against malaria prompts the urgent need to develop new intervention strategies. Whilst engineered symbiotic bacteria have been shown to confer mosquito resistance to parasite infection, a major challenge for field implementation is to ... |
|
|
Engineering a Culturable Serratia symbiotica Strain for Aphid ParatransgenesisK. M. Elston, J. Perreau, G. P. Maeda, N. A. Moran and J. E. Barrick, Applied Environmental Microbiology, 87. 2020.
Aphids are global agricultural pests and important models for bacterial symbiosis. To date, none of the native symbionts of aphids have been genetically manipulated, which limits our understanding of how they interact with their hosts. Serratia symbiotica CWBI-2.3(T) is a ... |
|
|
Microbiome Innovation in Agriculture: Development of Microbial Based Tools for Insect Pest ManagementM. Qadri, S. Short, K. Gast, J. Hernandez and A. C.-N. Wong, Frontiers in Sustainable Food Systems, 4. 2020.
This review emphasizes the potential and use of microbes in sustainable insect pest management. We first review the diverse insect traits shaped by insect-microbe associations that span nutrition, immunity, ecological interactions with natural enemy, insecticide resistance, and ... |
|
|
A transatlantic perspective on 20 emerging issues in biological engineeringWintle, BCB, C. R.; Rhodes, C.; Molloy, J. C.; Millett, P.; Adam, L.; Breitling, R.; Carlson, R.; Casagrande, R.; Dando, M.; Doubleday, R.; Drexler, E.; Edwards, B.; Ellis, T.; Evans, N. G.; Hammond, R.; Haseloff, J.; Kahl, L.; Kuiken, T.; Lichman, B. R.; Matthewman, C. A.; Napier, J. A.; OhEigeartaigh, S. S.; Patron, N. J.; Perello, E.; Shapira, P.; Tait, J.; Takano, E.; Sutherland, W. J., eLife, 6:21. 2017.
Advances in biological engineering are likely to have substantial impacts on global society. To explore these potential impacts we ran a horizon scanning exercise to capture a range of perspectives on the opportunities and risks presented by biological engineering. We first ... |
