Gene drive inhibition by the anti-CRISPR proteins AcrIIA2 and AcrIIA4 in Saccharomyces cerevisiaeBasgall, EMG, S. C.; Goeckel, M. E.; Giersch, R. M.; Roggenkamp, E.; Schrock, M. N.; Halloran, M.; Finnigan, G. C., Microbiology-Sgm, 164:464-474. 2018.
Given the widespread use and application of the clustered regularly interspaced short palindromic repeats (CRISPR)/Cas gene editing system across many fields, a major focus has been the development, engineering and discovery of molecular means to precisely control and regulate ...
Keywords: anti-CRISPR, biotechnology, Cas9, CRISPR, Gene drive, gene drive mechanisms, gene drive synthetic, Microbiology, modulation, plants, regulating gene drives, sgRNA, synthetic homing drive, system, toolkit, versatile, yeast
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